5ZIU

Crystal structure of human Entervirus D68 RdRp


Domain Annotation: SCOP Classification SCOP Database (version: 2.0) Homepage

ChainDomainClassArchitectureTopologyHomology
A3.30.70.270 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Reverse transcriptase/Diguanylate cyclase domain
A3.30.70.270 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Reverse transcriptase/Diguanylate cyclase domain
A1.20.960.20 Mainly Alpha Up-down Bundle Mitochondrial Import Receptor Subunit Tom20 Chain A

Protein Family Annotation Pfam Database Homepage

ChainsAccessionIdentifierDescriptionCommentsSource
APF00910RNA helicase (RNA_helicase)RNA helicaseThis family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.Domain
APF005483C cysteine protease (picornain 3C) (Peptidase_C3)3C cysteine protease (picornain 3C)- Family
APF00947Picornavirus core protein 2A (Pico_P2A)Picornavirus core protein 2AThis protein is a protease, involved in cleavage of the polyprotein.Domain
APF00073picornavirus capsid protein (Rhv)picornavirus capsid proteinCAUTION: This alignment is very weak. It can not be generated by clustalw. If a representative set is used for a seed, many so-called members are not recognised. The family should probably be split up into sub-families. Capsid proteins of picornavi ...CAUTION: This alignment is very weak. It can not be generated by clustalw. If a representative set is used for a seed, many so-called members are not recognised. The family should probably be split up into sub-families. Capsid proteins of picornaviruses. Picornaviruses are non-enveloped plus-strand ssRNA animal viruses with icosahedral capsids. They include rhinovirus (common cold) and poliovirus. Common structure is an 8-stranded beta sandwich. Variations (one or two extra strands) occur.
Domain
APF00680Viral RNA-dependent RNA polymerase (RdRP_1)Viral RNA-dependent RNA polymerase- Family
APF08727Poliovirus 3A protein like (P3A)Poliovirus 3A protein likeThis domain is found in positive-strand RNA viruses. The 3A protein is a critical component of the poliovirus replication complex, and is also an inhibitor of host cell ER to Golgi transport.Domain
APF01552Picornavirus 2B protein (Pico_P2B)Picornavirus 2B protein- Family
APF02226Picornavirus coat protein (VP4) (Pico_P1A)Picornavirus coat protein (VP4)- Family

Gene Product Annotation Gene Product Annotation

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
ARdRp