Chemical Component Summary

NameD-PROLINE
Identifiers(2R)-pyrrolidine-2-carboxylic acid
FormulaC5 H9 N O2
Molecular Weight115.13
TypeD-PEPTIDE LINKING
Isomeric SMILESOC(=O)[C@H]1CCCN1
InChIInChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1
InChIKeyONIBWKKTOPOVIA-SCSAIBSYSA-N

Chemical Details

Formal Charge0
Atom Count17
Chiral Atom Count1
Bond Count17
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB02853 
NameD-Proline
Groupsexperimental
DescriptionD-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva [A19262]. These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity [A19263].
Synonyms
  • DPR
  • D-Prolin
  • (R)-pyrrolidine-2-carboxylic acid
  • (R)-2-Carboxypyrrolidine
  • (2R)-pyrrolidine-2-carboxylic acid
CAS number344-25-2

Drug Targets

NameTarget SequencePharmacological ActionActions
Proton-coupled amino acid transporter 1MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWF...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682