Chemical Component Summary

NameGUANOSINE-5'-MONOPHOSPHATE
Identifiers[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate
FormulaC10 H14 N5 O8 P
Molecular Weight363.22
TypeRNA LINKING
Isomeric SMILESNC1=Nc2n(cnc2C(=O)N1)[C@@H]3O[C@H](CO[P](O)(O)=O)[C@@H](O)[C@H]3O
InChIInChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKeyRQFCJASXJCIDSX-UUOKFMHZSA-N

Chemical Details

Formal Charge0
Atom Count38
Chiral Atom Count4
Bond Count40
Aromatic Bond Count5

Drug Info: DrugBank

DrugBank IDDB01972 
NameGuanosine-5'-Monophosphate
Groupsexperimental
DescriptionGuanosine 5'-monophosphate. A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. [PubChem]
SynonymsGuanosine-5'-Monophosphate
CAS number85-32-5

Drug Targets

NameTarget SequencePharmacological ActionActions
Guanylate kinaseMSGPRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENG...unknown
Response regulator PleDMSARILVVDDIEANVRLLEAKLTAEYYEVSTAMDGPTALAMAARDLPDII...unknown
DNA polymeraseMKEFYLTVEQIGDSIFERYIDSNGRERTREVEYKPSLFAHCPESQATKYF...unknown
Disks large homolog 4MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGY...unknown
GMP reductase 1MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPI...unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682