5DK3

Crystal Structure of Pembrolizumab, a full length IgG4 antibody


Sequence Similarity Clusters for the Entities in PDB 5DK3

Entity #1 | Chains: A,F
Light Chain protein, length: 218 (BLAST)
Sequence Similarity Cutoff Rank Chains in Cluster Cluster ID / Name
100 % 2 3 16616
95 % 2 3 17554
90 % 94 296 66
70 % 886 2682 2
50 % 2307 6927 1
40 % 2308 6928 1
30 % 2324 6975 1
Entity #2 | Chains: B,G
Heavy Chain protein, length: 444 (BLAST)
Sequence Similarity Cutoff Rank Chains in Cluster Cluster ID / Name
100 % 1 1 49389
95 % 1 1 44423
90 % 1 1 42542
70 % 3 10 4684
50 % 4 27 1454
40 % 4 33 1084
30 % 4 33 1144

Instructions

In the table for each entity, view a list of similar sequences by selecting the link associated with the percentage cutoff.



View more detailed documentation on the redundancy reduction and sequence clustering procedure used by RCSB PDB.

You can also use the structure comparison tool to compare any 2 given structures


ACTION - (A) Select for download / view details OR (B) Select two chains for comparison
Rank PDB ID Entity ID Chains Description Details Taxonomy EC Number
1 6GFE 1 H, K Immunoglobulin gamma-4 heavy chain 9606
2 6RNN 2 D, H Immunoglobulin heavy chain 10090
3 6RCS 1 A R5.016 heavy chain 9606
4 5DK3 2 B, G Heavy Chain 9606
5 4WEB 2 H Mouse Fab Heavy Chain 10090
6 1IGT 2 B, D IGG2A INTACT ANTIBODY - MAB231 10090
7 1HZH 1 H, K IMMUNOGLOBULIN HEAVY CHAIN 9606
8 2IG2 2 H IGG1-LAMBDA KOL FAB (HEAVY CHAIN) 9606
9 1IGY 2 B, D IGG1 INTACT ANTIBODY MAB61.1.3 10090
10 1MCO 2 H IGG1 MCG INTACT ANTIBODY (HEAVY CHAIN) 9606
11 6S3T 3 D, E, N, R Immunoglobulin heavy chain 10090
12 6RCV 5 E, J R5.016 heavy chain 9606
13 6RCU 5 E R5.016 heavy chain 9606
14 6X3S 5 J, K IgG2b Fab Heavy Chain 10090
15 6X3T 5 J, K IgG2b Fab Heavy Chain 10090
16 6X3U 5 J, K IgG2b Fab Heavy Chain 10090
17 6X3V 5 J, K IgG2b Fab Heavy Chain 10090
18 6X3W 5 J, K IgG2b Fab Heavy Chain 10090
19 6X3X 5 J, K IgG2b Fab Heavy Chain 10090
20 6X3Z 5 J, K IgG2b Fab Heavy Chain 10090
21 6X40 5 J, K IgG2b Fab Heavy Chain 10090
22 7C2L 2 H, I, J heavy chain of 4A8 9606
23 6UDJ 4 D, H, N 1-18 Fab Heavy Chain 9606
24 6D6T 5 J, K IgG2b Fab Heavy Chain 10090
25 6D6U 5 J, K IgG2b Fab Heavy Chain 10090
26 6CNJ 4 G, I, K IgG1 Heavy Chain 10090
27 6CNK 4 G, K IgG1 Heavy Chain 10090