6G1D

Corynebacterium glutamicum OxyR C206 mutant

  • Classification: TRANSCRIPTION
  • Expression System: Escherichia coli
  • Mutation(s): 

  • Deposited: 2018-03-21 Released: 2018-12-05 
  • Deposition Author(s): Young, D.R., Pedre, B.P., Messens, J.M.
  • Funding Organization(s): VIB; IWT; Hercules; FWO; VUB Strategic Research Programme; Junta de Castilla y Leon; University of Leon 

Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.992 Å
  • R-Value Free: 0.221 
  • R-Value Work: 0.200 

wwPDB Validation 3D Report Full Report


This is version 1.0 of the entry. See complete history

Literature

Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2sensing.

Pedre, B.Young, D.Charlier, D.Mourenza, A.Rosado, L.A.Marcos-Pascual, L.Wahni, K.Martens, E.G de la Rubia, A.Belousov, V.V.Mateos, L.M.Messens, J.

(2018) Proc. Natl. Acad. Sci. U.S.A. --: --


Macromolecules

Find similar proteins by: Sequence  |  Structure

Entity ID: 1
MoleculeChainsSequence LengthOrganismDetails
Hydrogen peroxide-inducible genes activator
C, D, B, A
329N/AMutation(s): 1 
Protein Feature View is not available: No corresponding UniProt sequence found.
Small Molecules
Ligands 6 Unique
IDChainsName / Formula / InChI Key2D Diagram3D Interactions
NA
Query on NA

Download SDF File 
Download CCD File 
A
SODIUM ION
Na
FKNQFGJONOIPTF-UHFFFAOYSA-N
 Ligand Interaction
SO4
Query on SO4

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Download CCD File 
A, B, C, D
SULFATE ION
O4 S
QAOWNCQODCNURD-UHFFFAOYSA-L
 Ligand Interaction
FMT
Query on FMT

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Download CCD File 
B, C
FORMIC ACID
C H2 O2
BDAGIHXWWSANSR-UHFFFAOYSA-N
 Ligand Interaction
EDO
Query on EDO

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Download CCD File 
A, C, D
1,2-ETHANEDIOL
ETHYLENE GLYCOL
C2 H6 O2
LYCAIKOWRPUZTN-UHFFFAOYSA-N
 Ligand Interaction
PEG
Query on PEG

Download SDF File 
Download CCD File 
C, D
DI(HYDROXYETHYL)ETHER
C4 H10 O3
MTHSVFCYNBDYFN-UHFFFAOYSA-N
 Ligand Interaction
FOR
Query on FOR

Download SDF File 
Download CCD File 
A
FORMYL GROUP
C H2 O
WSFSSNUMVMOOMR-UHFFFAOYSA-N
 Ligand Interaction
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.992 Å
  • R-Value Free: 0.221 
  • R-Value Work: 0.200 
  • Space Group: P 1 21 1
Unit Cell:
Length (Å)Angle (°)
a = 74.409α = 90.00
b = 63.481β = 97.79
c = 157.414γ = 90.00
Software Package:
Software NamePurpose
Aimlessdata scaling
PHASERphasing
PHENIXrefinement
XDSdata reduction

Structure Validation

View Full Validation Report or Ramachandran Plots



Entry History & Funding Information

Deposition Data


Funding OrganizationLocationGrant Number
VIBBelgium--
IWTBelgium--
HerculesBelgiumHERC16
FWOBelgiumG.0D79.14N
VUB Strategic Research ProgrammeBelgiumSRP34
Junta de Castilla y LeonSpainLE326U14
University of LeonSpainUXXI2016/00127

Revision History 

  • Version 1.0: 2018-12-05
    Type: Initial release