6HIN

Mouse serotonin 5-HT3 receptor, serotonin-bound, F conformation


Experimental Data Snapshot

  • Method: ELECTRON MICROSCOPY
  • Resolution: 4.1 Å
  • Aggregation State: PARTICLE 
  • Reconstruction Method: SINGLE PARTICLE 

wwPDB Validation 3D Report Full Report


This is version 1.1 of the entry. See complete history

Literature

Conformational transitions of the serotonin 5-HT3receptor.

Polovinkin, L.Hassaine, G.Perot, J.Neumann, E.Jensen, A.A.Lefebvre, S.N.Corringer, P.J.Neyton, J.Chipot, C.Dehez, F.Schoehn, G.Nury, H.

(2018) Nature 563: 275-279


Macromolecules

Find similar proteins by: Sequence  |  Structure

Entity ID: 1
MoleculeChainsSequence LengthOrganismDetails
5-hydroxytryptamine receptor 3A
A, B, C, D, E
450Mus musculusMutation(s): 0 
Gene Names: Htr3a
Membrane protein
mpstruct
Group: 
TRANSMEMBRANE PROTEINS: ALPHA-HELICAL
Sub Group: 
Cys-Loop Receptor Family
Protein: 
Serotonin 5-HT3A receptor
Find proteins for E9QLC0 (Mus musculus)
Go to UniProtKB:  E9QLC0
Small Molecules
Ligands 2 Unique
IDChainsName / Formula / InChI Key2D Diagram3D Interactions
SRO
Query on SRO

Download SDF File 
Download CCD File 
A, B, C, D, E
SEROTONIN
3-(2-AMINOETHYL)-1H-INDOL-5-OL
C10 H12 N2 O
QZAYGJVTTNCVMB-UHFFFAOYSA-N
 Ligand Interaction
NAG
Query on NAG

Download SDF File 
Download CCD File 
A, B, C, D, E
N-ACETYL-D-GLUCOSAMINE
C8 H15 N O6
OVRNDRQMDRJTHS-FMDGEEDCSA-N
 Ligand Interaction
Experimental Data & Validation

Experimental Data

  • Method: ELECTRON MICROSCOPY
  • Resolution: 4.1 Å
  • Aggregation State: PARTICLE 
  • Reconstruction Method: SINGLE PARTICLE 

Structure Validation

View Full Validation Report or Ramachandran Plots



Entry History 

Deposition Data

Revision History 

  • Version 1.0: 2018-11-07
    Type: Initial release
  • Version 1.1: 2018-11-21
    Type: Data collection, Database references