6HIS

Mouse serotonin 5-HT3 receptor, tropisetron-bound, T conformation


Experimental Data Snapshot

  • Method: ELECTRON MICROSCOPY
  • Resolution: 4.5 Å
  • Aggregation State: PARTICLE 
  • Reconstruction Method: SINGLE PARTICLE 

wwPDB Validation 3D Report Full Report


This is version 1.0 of the entry. See complete history

Literature

Conformational transitions of the serotonin 5-HT3 receptor

Polovinkin, L.Hassaine, G.Perot, J.Neumann, E.Jensen, A.A.Lefebvre, S.N.Corringer, P.J.Neyton, J.Chipot, C.Dehez, F.Schoehn, G.Nury, H.

(2018) Nature --: --


Macromolecules

Find similar proteins by: Sequence  |  Structure

Entity ID: 1
MoleculeChainsSequence LengthOrganismDetails
5-hydroxytryptamine receptor 3A
A, E, B, C, D
445Mus musculusMutation(s): 0 
Gene Names: Htr3a (5ht3, Htr3)
Find proteins for P23979 (Mus musculus)
Go to UniProtKB:  P23979
Small Molecules
Ligands 3 Unique
IDChainsName / Formula / InChI Key2D Diagram3D Interactions
BMA
Query on BMA

Download SDF File 
Download CCD File 
A, B, C, D, E
BETA-D-MANNOSE
C6 H12 O6
WQZGKKKJIJFFOK-RWOPYEJCSA-N
 Ligand Interaction
TKT
Query on TKT

Download SDF File 
Download CCD File 
A, B, C, D, E
(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-INDOLE-3-CARBOXYLATE
TROPISETRON
C17 H20 N2 O2
ZNRGQMMCGHDTEI-ITGUQSILSA-N
 Ligand Interaction
NAG
Query on NAG

Download SDF File 
Download CCD File 
A, B, C, D, E
N-ACETYL-D-GLUCOSAMINE
C8 H15 N O6
OVRNDRQMDRJTHS-FMDGEEDCSA-N
 Ligand Interaction
Experimental Data & Validation

Experimental Data

  • Method: ELECTRON MICROSCOPY
  • Resolution: 4.5 Å
  • Aggregation State: PARTICLE 
  • Reconstruction Method: SINGLE PARTICLE 

Structure Validation

View Full Validation Report or Ramachandran Plots



Entry History 

Deposition Data

Revision History 

  • Version 1.0: 2018-11-07
    Type: Initial release