6MST

Cryo-EM structure of human AA amyloid fibril


Experimental Data Snapshot

  • Method: ELECTRON MICROSCOPY
  • Resolution: 2.7 Å
  • Aggregation State: HELICAL ARRAY 
  • Reconstruction Method: HELICAL 

wwPDB Validation 3D Report Full Report


This is version 1.0 of the entry. See complete history

Literature

Cryo-EM fibril structures from systemic amyloidosis provide insights into the species barrier of prion-like cross-seeding

Liberta, F.Loerch, S.Rennegarbe, M.Schierhorn, A.Westermark, P.Westermark, G.T.Hazenberg, B.P.C.Grigorieff, N.Fandrich, M.Schmidt, M.

To be published.

Macromolecules

Find similar proteins by: Sequence  |  Structure

Entity ID: 1
MoleculeChainsSequence LengthOrganismDetails
Serum amyloid A-1 protein
A, B, C, E, D, F, H, I, J, K, L, G
66Homo sapiensMutation(s): 0 
Gene Names: SAA1
Find proteins for P0DJI8 (Homo sapiens)
Go to Gene View: SAA1
Go to UniProtKB:  P0DJI8
Experimental Data & Validation

Experimental Data

  • Method: ELECTRON MICROSCOPY
  • Resolution: 2.7 Å
  • Aggregation State: HELICAL ARRAY 
  • Reconstruction Method: HELICAL 

Structure Validation

View Full Validation Report or Ramachandran Plots



Entry History & Funding Information

Deposition Data


Funding OrganizationLocationGrant Number
GermanyDFG FA 456/15-1
GermanyDFG SCHM 3276/1

Revision History 

  • Version 1.0: 2019-03-13
    Type: Initial release