6ZD5

Crystal structure of YTHDC1 S378A mutant complex with m6A


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.30 Å
  • R-Value Free: 0.233 
  • R-Value Work: 0.186 
  • R-Value Observed: 0.188 

wwPDB Validation   3D Report Full Report



Literature

Crystal structure of YTHDC1 with compound DHU_DC1_135

Bedi, R.K.Huang, D.Wiedmer, L.Caflisch, A.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  Structure
Entity ID: 1
MoleculeChainsSequence LengthOrganismDetailsImage
YTH domain containing 1AB183Homo sapiensMutation(s): 0 
Gene Names: YTHDC1
Protein Feature View
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.30 Å
  • R-Value Free: 0.233 
  • R-Value Work: 0.186 
  • R-Value Observed: 0.188 
  • Space Group: P 1 21 1
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 39.82α = 90
b = 103.4β = 105.765
c = 42.49γ = 90
Software Package:
Software NamePurpose
XDSdata reduction
XSCALEdata scaling
PHASERphasing
PHENIXrefinement

Structure Validation

View Full Validation Report



Entry History & Funding Information

Deposition Data


Funding OrganizationLocationGrant Number
Swiss National Science FoundationSwitzerland310030B_189363
Swedish Research CouncilSwedenVR 2019-00608

Revision History 

  • Version 1.0: 2021-01-13
    Type: Initial release