7JGG

Cryo-EM structure of P. falciparum VAR2CSA NF45 DBL5 and DBL6 domains at 4.88 A


Experimental Data Snapshot

  • Method: ELECTRON MICROSCOPY
  • Resolution: 4.88 Å
  • Aggregation State: PARTICLE 
  • Reconstruction Method: SINGLE PARTICLE 

wwPDB Validation   3D Report Full Report



Literature

Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA

Ma, R.Lian, T.Huang, R.Renn, J.P.Peterson, J.D.Zimmerberg, J.Duffy, P.E.Tolia, N.H.

(2021) Nat Microbiol 


Macromolecules
Find similar proteins by:  (by identity cutoff)  |  Structure
Entity ID: 1
MoleculeChainsSequence LengthOrganismDetailsImage
Erythrocyte membrane protein 1A2653Plasmodium falciparum NF54Mutation(s): 0 
Gene Names: PFNF54_03544
Find proteins for W7K270 (Plasmodium falciparum (isolate NF54))
Explore W7K270 
Go to UniProtKB:  W7K270
Protein Feature View
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: ELECTRON MICROSCOPY
  • Resolution: 4.88 Å
  • Aggregation State: PARTICLE 
  • Reconstruction Method: SINGLE PARTICLE 

Structure Validation

View Full Validation Report



Entry History & Funding Information

Deposition Data

  • Deposited Date: 2020-07-19 
  • Released Date: 2021-01-13 
  • Deposition Author(s): Ma, R., Tolia, N.H.

Funding OrganizationLocationGrant Number
National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)United States1 ZIA AI001237

Revision History 

  • Version 1.0: 2021-01-13
    Type: Initial release