1OC6

structure native of the D405N mutant of the CELLOBIOHYDROLASE CEL6A FROM HUMICOLA INSOLENS at 1.5 angstrom resolution

Present annotations:

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Product Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1oc6a_	Alpha and beta proteins (a/b)	7-stranded beta/alpha barrel	Glycosyl hydrolases family 6, cellulases	Glycosyl hydrolases family 6, cellulases	Cellobiohydrolase II (Cel6)	(Humicola insolens ) [TaxId: 34413 ]	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Glyco_hydro_6	e1oc6A1	A: a/b barrels	X: TIM beta/alpha-barrel	H: Cellulases (From Topology)	T: Cellulases	F: Glyco_hydro_6	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.20.20.40	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	1, 4-beta cellobiohydrolase	CATH (4.2.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Identifier	Description	Comments	Source
A	PF01341	Glycosyl hydrolases family 6 (Glyco_hydro_6)	Glycosyl hydrolases family 6	-	Domain

Gene Product Annotation Gene Product Annotation

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	CELLOBIOHYDROLASE II	catalytic activity hydrolase activity, hydrolyzing O-glycosyl compounds cellulose 1,4-beta-cellobiosidase activity hydrolase activity hydrolase activity, acting on glycosyl bonds binding carbohydrate binding polysaccharide binding cellulose binding		extracellular region cellular anatomical entity

RCSB PDB is funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.