1PHP

STRUCTURE OF THE ADP COMPLEX OF THE 3-PHOSPHOGLYCERATE KINASE FROM BACILLUS STEAROTHERMOPHILUS AT 1.65 ANGSTROMS

Present annotations:

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Product Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1phpa_	Alpha and beta proteins (a/b)	Phosphoglycerate kinase	Phosphoglycerate kinase	Phosphoglycerate kinase	Phosphoglycerate kinase	(Geobacillus stearothermophilus ) [TaxId: 1422 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Phosphoglycerate kinase	8020719	4000818	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Phosphoglycerate kinase	8033099	3001564	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PGK_N	e1phpA2	A: a/b three-layered sandwiches	X: Phosphoglycerate kinase domain 1 (From Topology)	H: Phosphoglycerate kinase domain 1 (From Topology)	T: Phosphoglycerate kinase domain 1	F: PGK_N	ECOD (1.6)
A	PGK_C	e1phpA1	A: a/b three-layered sandwiches	X: Phosphoglycerate kinase domain 2 (From Topology)	H: Phosphoglycerate kinase domain 2 (From Topology)	T: Phosphoglycerate kinase domain 2	F: PGK_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1260	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Phosphoglycerate kinase, N-terminal domain	CATH (4.2.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00162	Phosphoglycerate kinase (PGK)	Phosphoglycerate kinase	-	Domain

Gene Product Annotation Gene Product Annotation

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	3-PHOSPHOGLYCERATE KINASE	phosphoglycerate kinase activity kinase activity phosphotransferase activity, carboxyl group as acceptor transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding phosphoglycerate kinase activity kinase activity phosphotransferase activity, carboxyl group as acceptor transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding	phosphorylation cellular metabolic process phosphate-containing compound metabolic process metabolic process cellular process phosphorus metabolic process carbohydrate metabolic process pyruvate metabolic process catabolic process oxoacid metabolic process carbohydrate catabolic process carboxylic acid metabolic process primary metabolic process generation of precursor metabolites and energy phosphorylation cellular metabolic process phosphate-containing compound metabolic process metabolic process cellular process phosphorus metabolic process carbohydrate metabolic process pyruvate metabolic process catabolic process oxoacid metabolic process carbohydrate catabolic process carboxylic acid metabolic process primary metabolic process generation of precursor metabolites and energy organic acid metabolic process organic substance metabolic process glycolytic process small molecule metabolic process monocarboxylic acid metabolic process organic substance catabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.