Domain Annotation: SCOP/SCOPe Classification SCOP Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Dd4i5bd2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) Class II MHC alpha chain, C-terminal domain human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Dd4i5bd1 Alpha and beta proteins (a+b) MHC antigen-recognition domain MHC antigen-recognition domain MHC antigen-recognition domain Class II MHC alpha chain, N-terminal domain human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ad4i5ba2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) Class II MHC alpha chain, C-terminal domain human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ad4i5ba1 Alpha and beta proteins (a+b) MHC antigen-recognition domain MHC antigen-recognition domain MHC antigen-recognition domain Class II MHC alpha chain, N-terminal domain human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ed4i5be2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) Class II MHC beta chain, C-terminal domain human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ed4i5be1 Alpha and beta proteins (a+b) MHC antigen-recognition domain MHC antigen-recognition domain MHC antigen-recognition domain Class II MHC beta chain, N-terminal domain human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd4i5bb2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) Class II MHC beta chain, C-terminal domain human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd4i5bb1 Alpha and beta proteins (a+b) MHC antigen-recognition domain MHC antigen-recognition domain MHC antigen-recognition domain Class II MHC beta chain, N-terminal domain human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
DSCOP2B SuperfamilyMHC antigen-recognition domain8040455 3000521 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyImmunoglobulin (Ig) domain-like8054671 3000071 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMHC antigen-recognition domain8040455 3000521 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyImmunoglobulin (Ig) domain-like8054671 3000071 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyImmunoglobulin (Ig) domain-like8054705 3000071 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMHC antigen-recognition domain8034737 3000521 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMHC antigen-recognition domain8055636 3000521 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyImmunoglobulin (Ig) domain-like8054703 3000071 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyImmunoglobulin (Ig) domain-like8054703 3000071 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyImmunoglobulin (Ig) domain-like8054705 3000071 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMHC antigen-recognition domain8055636 3000521 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMHC antigen-recognition domain8034737 3000521 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
DC1-set_2e4i5bD1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
DMHC_II_alphae4i5bD2 A: a+b two layersX: MHC antigen-recognition domain (From Topology)H: MHC antigen-recognition domain (From Topology)T: MHC antigen-recognition domainF: MHC_II_alphaECOD (1.6)
AC1-set_2e4i5bA1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
AMHC_II_alphae4i5bA2 A: a+b two layersX: MHC antigen-recognition domain (From Topology)H: MHC antigen-recognition domain (From Topology)T: MHC antigen-recognition domainF: MHC_II_alphaECOD (1.6)
EC1-set_2e4i5bE1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
EMHC_II_betae4i5bE2 A: a+b two layersX: MHC antigen-recognition domain (From Topology)H: MHC antigen-recognition domain (From Topology)T: MHC antigen-recognition domainF: MHC_II_betaECOD (1.6)
BC1-set_2e4i5bB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
BMHC_II_betae4i5bB2 A: a+b two layersX: MHC antigen-recognition domain (From Topology)H: MHC antigen-recognition domain (From Topology)T: MHC antigen-recognition domainF: MHC_II_betaECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
A, D
MH2 HLA-DR1 II-ALPHA Homo sapiens (human) HLA-DRA*0101, HLA-DRA*0102 G-DOMAIN G-ALPHA, C-LIKE-DOMAIN C-LIKE MH MH2-ALPHA_BETA IMGT (202337-0)
B, E
MH2 HLA-DR1 II-BETA Homo sapiens (human) HLA-DRB1*0101 G-DOMAIN G-BETA, C-LIKE-DOMAIN C-LIKE MH MH2-ALPHA_BETA IMGT (202337-0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, D
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain
A, D
PF00993Class II histocompatibility antigen, alpha domain (MHC_II_alpha)Class II histocompatibility antigen, alpha domain- Domain
B, E
PF00969Class II histocompatibility antigen, beta domain (MHC_II_beta)Class II histocompatibility antigen, beta domain- Domain
B, E
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain

Gene Product Annotation Gene Product Annotation

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, D
HLA class II histocompatibility antigen, DR alpha chain
B, E
HLA class II histocompatibility antigen, DRB1-1 beta chain
C, F
truncated hemagglutinin peptidenonenonenone