Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilySIS domain/Ribosomal protein S2-like8052790 3001397 SCOP2B (2022-02-25)
BSCOP2B SuperfamilyRibosomal S3Ae-like8053208 3002166 SCOP2B (2022-02-25)
ESCOP2B SuperfamilyNucleic acid-binding proteins8052746 3000135 SCOP2B (2022-02-25)
ESCOP2B SuperfamilyTranslation proteins SH3-like KOW motif containing domain8052747 3000334 SCOP2B (2022-02-25)
ESCOP2B SuperfamilyAlpha-L RNA-binding motif8052745 3001473 SCOP2B (2022-02-25)
FSCOP2B SuperfamilyRibosomal protein S78066001 3000799 SCOP2B (2022-02-25)
ISCOP2B Superfamily50S Ribosomal protein L14-like8053075 3000433 SCOP2B (2022-02-25)
KSCOP2B SuperfamilyWinged helix DNA-binding domain8055712 3000034 SCOP2B (2022-02-25)
LSCOP2B SuperfamilyRibosomal S17 N-terminal domain-like8052708 3002138 SCOP2B (2022-02-25)
LSCOP2B SuperfamilyNucleic acid-binding proteins8052707 3000135 SCOP2B (2022-02-25)
MSCOP2B SuperfamilyL30e-like8063980 3001739 SCOP2B (2022-02-25)
NSCOP2B SuperfamilyHomeodomain-like8052970 3000001 SCOP2B (2022-02-25)
NSCOP2B SuperfamilyS15/NS1 RNA-binding domain8052971 3001284 SCOP2B (2022-02-25)
OSCOP2B SuperfamilyTranslational machinery components8097832 3000571 SCOP2B (2022-02-25)
QSCOP2B SuperfamilyRibosomal protein S5 domain 2-like8082683 3000100 SCOP2B (2022-02-25)
SSCOP2B SuperfamilyS13-like H2TH domain8101439 3000053 SCOP2B (2022-02-25)
TSCOP2B SuperfamilyWinged helix DNA-binding domain8089322 3000034 SCOP2B (2022-02-25)
USCOP2B SuperfamilyRibosomal protein S108097814 3001336 SCOP2B (2022-02-25)
WSCOP2B SuperfamilyRibosomal protein S88079081 3000709 SCOP2B (2022-02-25)
ZSCOP2B SuperfamilyWinged helix DNA-binding domain8090991 3000034 SCOP2B (2022-02-25)
AA [auth a]SCOP2B SuperfamilyGlucocorticoid receptor-like (DNA-binding domain)8053150 3000068 SCOP2B (2022-02-25)
CA [auth c]SCOP2B SuperfamilyNucleic acid-binding proteins8095265 3000135 SCOP2B (2022-02-25)
DA [auth d]SCOP2B SuperfamilyGlucocorticoid receptor-like (DNA-binding domain)8052584 3000068 SCOP2B (2022-02-25)
EA [auth e]SCOP2B SuperfamilyRibosomal protein S30e-like8053455 3002190 SCOP2B (2022-02-25)
GA [auth g]SCOP2B SuperfamilyWD40 repeat-like8097816 3001694 SCOP2B (2022-02-25)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ARibosomal_S2_2e4kzxA1 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Ribosomal protein S2/SIS domain (From Topology)T: Ribosomal protein S2/SIS domainF: Ribosomal_S2_2ECOD (1.6)
BRibosomal_S3Ae_Ne4kzxB1 A: beta barrelsX: Ribosomal protein L25-likeH: 40S ribosomal protein S3A N-terminal domain (From Topology)T: 40S ribosomal protein S3A N-terminal domainF: Ribosomal_S3Ae_NECOD (1.6)
BRibosomal_S3Ae_Ce4kzxB2 A: a+b two layersX: T-foldH: 40S ribosomal protein S3A C-terminal domain (From Topology)T: 40S ribosomal protein S3A C-terminal domainF: Ribosomal_S3Ae_CECOD (1.6)
CRibosomal_S5_C_1e4kzxC2 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: Ribosomal_S5_C_1ECOD (1.6)
CRibosomal_S5_3e4kzxC1 A: a+b two layersX: dsRBD-likeH: dsRNA-binding domain-like (From Topology)T: dsRNA-binding domain-likeF: Ribosomal_S5_3ECOD (1.6)
CRibosomal_S5_2e4kzxC3 A: extended segmentsX: N-terminal region in 40S ribosomal protein rpS2 (S5p) (From Topology)H: N-terminal region in 40S ribosomal protein rpS2 (S5p) (From Topology)T: N-terminal region in 40S ribosomal protein rpS2 (S5p)F: Ribosomal_S5_2ECOD (1.6)
DRibosomal_S3_Ce4kzxD1 A: a+b two layersX: T-foldH: Ribosomal protein S3-C (From Topology)T: Ribosomal protein S3-CF: Ribosomal_S3_CECOD (1.6)
DKH_2_3e4kzxD3 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: KH-domainsT: Prokaryotic type KH domain (KH-domain type II)F: KH_2_3ECOD (1.6)
ERibosomal_S4ee4kzxE2 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: Ribosomal_S4eECOD (1.6)
E40S_S4_Ce4kzxE1 A: beta barrelsX: SH3H: SH3T: SH3F: 40S_S4_CECOD (1.6)
ERS4NTe4kzxE3 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Alpha-L RNA-binding motifF: RS4NTECOD (1.6)
FRibosomal_S7_1e4kzxF1 A: alpha arraysX: Ribosomal protein S7 (From Topology)H: Ribosomal protein S7 (From Topology)T: Ribosomal protein S7F: Ribosomal_S7_1ECOD (1.6)
GRibosomal_S6ee4kzxG1 A: beta barrelsX: Ribosomal protein L25-likeH: Ribosomal protein L25-like (From Topology)T: Ribosomal protein L25-likeF: Ribosomal_S6eECOD (1.6)
HRibosomal_S7e_Ne4kzxH2 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: 40S ribosomal protein S7-A (From Topology)T: 40S ribosomal protein S7-AF: Ribosomal_S7e_NECOD (1.6)
HRibosomal_S7e_C_1e4kzxH1 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: 40S ribosomal protein S7-A (From Topology)T: 40S ribosomal protein S7-AF: Ribosomal_S7e_C_1ECOD (1.6)
IRibosomal_S8ee4kzxI1 A: beta barrelsX: Ribosomal protein L14-likeH: Ribosomal protein L14-related (From Topology)T: Ribosomal protein L14-relatedF: Ribosomal_S8eECOD (1.6)
JS4e4kzxJ1 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Alpha-L RNA-binding motifF: S4ECOD (1.6)
KS10_plectine4kzxK1 A: alpha arraysX: HTHH: HTHT: wingedF: S10_plectinECOD (1.6)
LRibosomal_S17_1e4kzxL1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: Ribosomal_S17_1ECOD (1.6)
MRibosomal_L7Aee4kzxM1 A: a+b three layersX: Bacillus chorismate mutase-likeH: L30e-like (From Topology)T: L30e-likeF: Ribosomal_L7AeECOD (1.6)
NRibosomal_S13_Ne4kzxN2 A: alpha arraysX: HTHH: 40S ribosomal protein S13 N-terminal domain (From Topology)T: 40S ribosomal protein S13 N-terminal domainF: Ribosomal_S13_NECOD (1.6)
NRibosomal_S15_2e4kzxN1 A: alpha arraysX: S15/NS1 RNA-binding domain (From Topology)H: S15/NS1 RNA-binding domain (From Topology)T: S15/NS1 RNA-binding domainF: Ribosomal_S15_2ECOD (1.6)
ORibosomal_S11e4kzxO1 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: Ribosomal_S11ECOD (1.6)
PRibosomal_S19e4kzxP1 A: a+b two layersX: Ribosomal protein S19 (From Topology)H: Ribosomal protein S19 (From Topology)T: Ribosomal protein S19F: Ribosomal_S19ECOD (1.6)
QRibosomal_S9e4kzxQ1 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: Ribosomal_S9ECOD (1.6)
RRibosomal_S17ee4kzxR1 A: alpha arraysX: HTHH: HTHT: FF domainF: Ribosomal_S17eECOD (1.6)
SRibosomal_S13e4kzxS1 A: alpha arraysX: HhH/H2THH: H2TH (From Topology)T: H2THF: Ribosomal_S13ECOD (1.6)
TRibosomal_S19ee4kzxT1 A: alpha arraysX: HTHH: HTHT: wingedF: Ribosomal_S19eECOD (1.6)
URibosomal_S10_1e4kzxU1 A: a+b two layersX: Alpha-beta plaitsH: Ribosomal protein S10 (From Topology)T: Ribosomal protein S10F: Ribosomal_S10_1ECOD (1.6)
VRibosomal_S21ee4kzxV1 A: a+b two layersX: 40S ribosomal protein rpS21 (S21e) (From Topology)H: 40S ribosomal protein rpS21 (S21e) (From Topology)T: 40S ribosomal protein rpS21 (S21e)F: Ribosomal_S21eECOD (1.6)
WRibosomal_S8_N_1e4kzxW1 A: a+b two layersX: R3H domain-likeH: Ribosomal protein S8, N-terminal domain (From Topology)T: Ribosomal protein S8, N-terminal domainF: Ribosomal_S8_N_1ECOD (1.6)
WRibosomal_S8_C_1e4kzxW2 A: a+b two layersX: Ribosomal protein S8, C-terminal domain (From Topology)H: Ribosomal protein S8, C-terminal domain (From Topology)T: Ribosomal protein S8, C-terminal domainF: Ribosomal_S8_C_1ECOD (1.6)
XRibosom_S12_S23e4kzxX1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: Ribosom_S12_S23ECOD (1.6)
YRibosomal_S24ee4kzxY1 A: a+b two layersX: Alpha-beta plaitsH: Ribosomal proteins S24e, L23 and L15e (From Topology)T: Ribosomal proteins S24e, L23 and L15eF: Ribosomal_S24eECOD (1.6)
ZRibosomal_S25e4kzxZ1 A: alpha arraysX: HTHH: HTHT: wingedF: Ribosomal_S25ECOD (1.6)
AA [auth a]Ribosomal_S26ee4kzxa1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: LIM domain-likeF: Ribosomal_S26eECOD (1.6)
BA [auth b]Ribosomal_S27ee4kzxb1 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: Ribosomal_S27eECOD (1.6)
CA [auth c]Ribosomal_S28ee4kzxc1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: Ribosomal_S28eECOD (1.6)
DA [auth d]Ribosomal_S14_2e4kzxd1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: LIM domain-likeF: Ribosomal_S14_2ECOD (1.6)
EA [auth e]Ribosomal_S30e4kzxe1 A: extended segmentsX: 40S ribosomal protein S30 (S30e) (From Topology)H: 40S ribosomal protein S30 (S30e) (From Topology)T: 40S ribosomal protein S30 (S30e)F: Ribosomal_S30ECOD (1.6)
FA [auth f]Ribosomal_S27e4kzxf1 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: Ribosomal_S27ECOD (1.6)
GA [auth g]DUF1899e4kzxg1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: DUF1899ECOD (1.6)
IA [auth l]SUI1e4kzxl1 A: a+b two layersX: Glucose permease domain IIB-likeH: eIF1-like (From Topology)T: eIF1-likeF: SUI1ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionIdentifierDescriptionCommentsSource
A PF00318Ribosomal protein S2 (Ribosomal_S2)Ribosomal protein S2- FamilyFamily
A PF1612240S ribosomal protein SA C-terminus (40S_SA_C)40S ribosomal protein SA C-terminus- FamilyFamily
B PF01015Ribosomal S3Ae family (Ribosomal_S3Ae)Ribosomal S3Ae family- FamilyFamily
C PF03719Ribosomal protein S5, C-terminal domain (Ribosomal_S5_C)Ribosomal protein S5, C-terminal domain- DomainDomain
C PF00333Ribosomal protein S5, N-terminal domain (Ribosomal_S5)Ribosomal protein S5, N-terminal domain- DomainDomain
D PF07650KH domain (KH_2)KH domain- DomainDomain
D PF00189Ribosomal protein S3, C-terminal domain (Ribosomal_S3_C)Ribosomal protein S3, C-terminal domainThis family contains a central domain Pfam:PF00013, hence the amino and carboxyl terminal domains are stored separately. This is a minimal carboxyl-terminal domain. Some are much longer.DomainDomain
E PF00900Ribosomal family S4e (Ribosomal_S4e)Ribosomal family S4e- FamilyFamily
E PF1612140S ribosomal protein S4 C-terminus (40S_S4_C)40S ribosomal protein S4 C-terminus- FamilyFamily
E PF08071RS4NT (NUC023) domain (RS4NT)RS4NT (NUC023) domainThis is the N-terminal domain of Ribosomal S4 / S4e proteins. This domain is associated with S4 and KOW domains [1].DomainDomain
E PF00467KOW motif (KOW)KOW motif- FamilyFamily
F PF00177Ribosomal protein S7p/S5e (Ribosomal_S7)Ribosomal protein S7p/S5eThis family contains ribosomal protein S7 from prokaryotes and S5 from eukaryotes.DomainDomain
G PF01092Ribosomal protein S6e (Ribosomal_S6e)Ribosomal protein S6e- FamilyFamily
H PF01251Ribosomal protein S7e (Ribosomal_S7e)Ribosomal protein S7e- FamilyFamily
I PF01201Ribosomal protein S8e (Ribosomal_S8e)Ribosomal protein S8e- FamilyFamily
J PF00163Ribosomal protein S4/S9 N-terminal domain (Ribosomal_S4)Ribosomal protein S4/S9 N-terminal domain- FamilyFamily
J PF01479S4 domain (S4)S4 domainThe S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ...The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation [1]. The S4 domain probably mediates binding to RNA.
DomainDomain
K PF03501Plectin/S10 domain (S10_plectin)Plectin/S10 domainThis presumed domain is found at the N-terminus of some isoforms of the cytoskeletal muscle protein plectin as well as the ribosomal S10 protein. This domain may be involved in RNA binding.DomainDomain
L PF16205Ribosomal_S17 N-terminal (Ribosomal_S17_N)Ribosomal_S17 N-terminal- FamilyFamily
L PF00366Ribosomal protein S17 (Ribosomal_S17)Ribosomal protein S17- DomainDomain
M PF01248Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (Ribosomal_L7Ae)Ribosomal protein L7Ae/L30e/S12e/Gadd45 familyThis family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD11 ...This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118 [1].
DomainDomain
N PF08069Ribosomal S13/S15 N-terminal domain (Ribosomal_S13_N)Ribosomal S13/S15 N-terminal domainThis domain is found at the N-terminus of ribosomal S13 and S15 proteins. This domain is also identified as NUC021 [1].DomainDomain
N PF00312Ribosomal protein S15 (Ribosomal_S15)Ribosomal protein S15- DomainDomain
O PF00411Ribosomal protein S11 (Ribosomal_S11)Ribosomal protein S11- FamilyFamily
P PF00203Ribosomal protein S19 (Ribosomal_S19)Ribosomal protein S19- DomainDomain
Q PF00380Ribosomal protein S9/S16 (Ribosomal_S9)Ribosomal protein S9/S16- FamilyFamily
R PF00833Ribosomal S17 (Ribosomal_S17e)Ribosomal S17- FamilyFamily
S PF00416Ribosomal protein S13/S18 (Ribosomal_S13)Ribosomal protein S13/S18- FamilyFamily
T PF01090Ribosomal protein S19e (Ribosomal_S19e)Ribosomal protein S19e- FamilyFamily
U PF00338Ribosomal protein S10p/S20e (Ribosomal_S10)Ribosomal protein S10p/S20eThis family includes small ribosomal subunit S10 from prokaryotes and S20 from eukaryotes.DomainDomain
V PF01249Ribosomal protein S21e (Ribosomal_S21e)Ribosomal protein S21e- FamilyFamily
W PF00410Ribosomal protein S8 (Ribosomal_S8)Ribosomal protein S8- DomainDomain
X PF00164Ribosomal protein S12/S23 (Ribosom_S12_S23)Ribosomal protein S12/S23- FamilyFamily
Y PF01282Ribosomal protein S24e (Ribosomal_S24e)Ribosomal protein S24e- FamilyFamily
Z PF03297S25 ribosomal protein (Ribosomal_S25)S25 ribosomal protein- FamilyFamily
AA [auth a]PF01283Ribosomal protein S26e (Ribosomal_S26e)Ribosomal protein S26e- FamilyFamily
BA [auth b]PF01667Ribosomal protein S27 (Ribosomal_S27e)Ribosomal protein S27- FamilyFamily
CA [auth c]PF01200Ribosomal protein S28e (Ribosomal_S28e)Ribosomal protein S28e- FamilyFamily
DA [auth d]PF00253Ribosomal protein S14p/S29e (Ribosomal_S14)Ribosomal protein S14p/S29e- FamilyFamily
EA [auth e]PF04758Ribosomal protein S30 (Ribosomal_S30)Ribosomal protein S30- FamilyFamily
FA [auth f]PF01599Ribosomal protein S27a (Ribosomal_S27)Ribosomal protein S27aThis family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesised as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins ...This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesised as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins as extensions of ubiquitin promotes their incorporation into nascent ribosomes by a transient metabolic stabilisation and is required for efficient ribosome biogenesis [3]. The ribosomal extension protein S27a contains a basic region that is proposed to form a zinc finger; its fusion gene is proposed as a mechanism to maintain a fixed ratio between ubiquitin necessary for degrading proteins and ribosomes a source of proteins [2].
DomainDomain
GA [auth g]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- RepeatRepeat
IA [auth l]PF01253Translation initiation factor SUI1 (SUI1)Translation initiation factor SUI1- DomainDomain

Gene Product Annotation Gene Product Annotation

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A 40S ribosomal protein SA
    B 40S ribosomal protein S3a
    C 40S ribosomal protein S2
      D 40S ribosomal protein S3
      E 40S ribosomal protein S4X
        F 40S ribosomal protein S5
          G 40S ribosomal protein S6
            H 40S ribosomal protein S7
              I 40S ribosomal protein S8
                J 40S Ribosomal protein S9
                  K 40S ribosomal protein S10
                      L 40S ribosomal protein S11
                        M 40S ribosomal protein S12
                          N 40S ribosomal protein S13
                            O 40S ribosomal protein S14
                              P 40S ribosomal protein S15
                              Q 40S ribosomal protein S16
                              R 40S ribosomal protein S17
                                S 40S ribosomal protein S18
                                  T 40S ribosomal protein S19
                                    U 40S ribosomal protein S20
                                      V 40S ribosomal protein S21
                                        W 40S ribosomal protein S15A
                                          X 40S ribosomal protein S23
                                            Y 40S ribosomal protein S24
                                              Z 40S ribosomal protein S25
                                              AA [auth a]40S ribosomal protein S26
                                                BA [auth b]40S ribosomal protein S27
                                                  CA [auth c]40S ribosomal protein S28
                                                  DA [auth d]40S ribosomal protein S29
                                                    EA [auth e]40S ribosomal protein S30
                                                      FA [auth f]40S ribosomal protein S27A
                                                        GA [auth g]40S ribosomal protein RACK1
                                                          HA [auth i]18S ribosomal RNAnonenonenone
                                                          IA [auth l]Eukaryotic translation initiation factor 1