Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyPurS-like8039955 3000512 SCOP2B (2022-02-25)
ASCOP2B SuperfamilyPurM N-terminal domain-like8039957 3001759 SCOP2B (2022-02-25)
ASCOP2B SuperfamilyPurM C-terminal domain-like8039959 3000696 SCOP2B (2022-02-25)
ASCOP2B SuperfamilyPurM N-terminal domain-like8039956 3001759 SCOP2B (2022-02-25)
ASCOP2B SuperfamilyPurM C-terminal domain-like8039960 3000696 SCOP2B (2022-02-25)
ASCOP2B SuperfamilyClass I glutamine amidotransferase-like8039953 3001405 SCOP2B (2022-02-25)
ASCOP2B SuperfamilyFGAM synthase PurL linker domain8039952 3001116 SCOP2B (2022-02-25)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APRK05297_2nde4lgyA1 A: alpha arraysX: RuvA-CH: FGAM synthase PurL, linker domain (From Topology)T: FGAM synthase PurL, linker domainF: PRK05297_2ndECOD (1.6)
APRK05297_1ste4lgyA2 A: a+b two layersX: Alpha-beta plaitsH: PurS-like (From Topology)T: PurS-likeF: PRK05297_1stECOD (1.6)
AAIRS_Ce4lgyA3 A: a+b two layersX: Alpha-beta plaitsH: PurM C-terminal domain-like (From Topology)T: PurM C-terminal domain-likeF: AIRS_CECOD (1.6)
AAIRSe4lgyA6 A: a+b three layersX: Bacillus chorismate mutase-likeH: PurM N-terminal domain-like (From Topology)T: PurM N-terminal domain-likeF: AIRSECOD (1.6)
AAIRS_1e4lgyA5 A: a+b three layersX: Bacillus chorismate mutase-likeH: PurM N-terminal domain-like (From Topology)T: PurM N-terminal domain-likeF: AIRS_1ECOD (1.6)
AGATase_5e4lgyA7 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Class I glutamine amidotransferase-likeT: Class I glutamine amidotransferase-likeF: GATase_5ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A1.10.8.750 Mainly Alpha Orthogonal Bundle Helicase, Ruva Protein domain 3CATH (4.2.0)
A3.40.50.880 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Class I glutamine amidotransferase (GATase) domainCATH (4.2.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionIdentifierDescriptionCommentsSource
A PF18076Formylglycinamide ribonucleotide amidotransferase N-terminal (FGAR-AT_N)Formylglycinamide ribonucleotide amidotransferase N-terminalThis is the N-terminal domain found in Formylglycinamide ribonucleotide amidotransferase (FGAR-AT), also known as Phosphoribosylformylglycinamidine synthase (EC:6.3.5.3), PurL and formylglycinamidine ribonucleotide (FGAM) synthase. This enzyme cataly ...This is the N-terminal domain found in Formylglycinamide ribonucleotide amidotransferase (FGAR-AT), also known as Phosphoribosylformylglycinamidine synthase (EC:6.3.5.3), PurL and formylglycinamidine ribonucleotide (FGAM) synthase. This enzyme catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide and glutamine to formylglycinamidine ribonucleotide, ADP, Pi, and glutamate in the fourth step of the purine biosynthetic pathway [3].
Domain
A PF02769AIR synthase related protein, C-terminal domain (AIRS_C)AIR synthase related protein, C-terminal domainThis family includes Hydrogen expression/formation protein HypE Swiss:P24193, AIR synthases Swiss:P08178 EC:6.3.3.1, FGAM synthase Swiss:P35852 EC:6.3.5.3 and selenide, water dikinase Swiss:P16456 EC:2.7.9.3. The function of the C-terminal domain of ...This family includes Hydrogen expression/formation protein HypE Swiss:P24193, AIR synthases Swiss:P08178 EC:6.3.3.1, FGAM synthase Swiss:P35852 EC:6.3.5.3 and selenide, water dikinase Swiss:P16456 EC:2.7.9.3. The function of the C-terminal domain of AIR synthase is unclear, but the cleft formed between N and C domains is postulated as a sulphate binding site [1].
Domain
A PF13507CobB/CobQ-like glutamine amidotransferase domain (GATase_5)CobB/CobQ-like glutamine amidotransferase domainThis family captures members that are not found in Pfam:PF00310, Pfam:PF07685 and Pfam:PF13230.Domain
A PF18072Formylglycinamide ribonucleotide amidotransferase linker domain (FGAR-AT_linker)Formylglycinamide ribonucleotide amidotransferase linker domainThis is the linker domain found in Formylglycinamide ribonucleotide amidotransferase (FGAR-AT), also known as Phosphoribosylformylglycinamidine synthase (EC:6.3.5.3), PurL and formylglycinamidine ribonucleotide (FGAM) synthase. This enzyme catalyzes ...This is the linker domain found in Formylglycinamide ribonucleotide amidotransferase (FGAR-AT), also known as Phosphoribosylformylglycinamidine synthase (EC:6.3.5.3), PurL and formylglycinamidine ribonucleotide (FGAM) synthase. This enzyme catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, Pi, and glutamate in the fourth step of the purine biosynthetic pathway. The structure analysis of Salmonella typhimurium FGAR-AT reveals that this linker domain is made up of a long hydrophilic belt with an extended conformation [4].
Domain