6D4O
Eubacterium eligens beta-glucuronidase bound to an amoxapine-glucuronide conjugate
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d6d4oa2 | All beta proteins | Immunoglobulin-like beta-sandwich | beta-Galactosidase/glucuronidase domain | automated matches | automated matches | (Lachnospira eligens ) [TaxId: 39485 ], | SCOPe (2.08) |
A | d6d4oa1 | All beta proteins | Galactose-binding domain-like | Galactose-binding domain-like | automated matches | automated matches | (Lachnospira eligens ) [TaxId: 39485 ], | SCOPe (2.08) |
A | d6d4oa3 | Alpha and beta proteins (a/b) | TIM beta/alpha-barrel | (Trans)glycosidases | automated matches | automated matches | (Lachnospira eligens ) [TaxId: 39485 ], | SCOPe (2.08) |
A | d6d4oa4 | Artifacts | Tags | Tags | Tags | N-terminal Tags | (Lachnospira eligens ) [TaxId: 39485 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Glyco_hydro_2_N | e6d4oA1 | A: beta sandwiches | X: jelly-roll | H: Concanavalin A-like | T: Galactose-binding domain-like | F: Glyco_hydro_2_N | ECOD (1.6) |
A | Glyco_hydro_2 | e6d4oA3 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: Glyco_hydro_2 | ECOD (1.6) |
A | Glyco_hydro_2_C | e6d4oA2 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Glyco_hydro_2_C | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 2.60.120.260 | Mainly Beta | Sandwich | Jelly Rolls | Galactose-binding domain-like | CATH (utative) |
A | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (utative) |
A | 3.20.20.80 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Glycosidases | CATH (utative) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF02836 | Glycosyl hydrolases family 2, TIM barrel domain (Glyco_hydro_2_C) | Glycosyl hydrolases family 2, TIM barrel domain | This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities. | Domain | |
PF00703 | Glycosyl hydrolases family 2 (Glyco_hydro_2) | Glycosyl hydrolases family 2 | This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities. | Domain | |
PF02837 | Glycosyl hydrolases family 2, sugar binding domain (Glyco_hydro_2_N) | Glycosyl hydrolases family 2, sugar binding domain | This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|---|---|---|---|
Beta-glucuronidase | - |
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR017853 | Glycoside hydrolase superfamily | Homologous Superfamily | |
IPR006101 | Glycoside hydrolase, family 2 | Family | |
IPR008979 | Galactose-binding-like domain superfamily | Homologous Superfamily | |
IPR006102 | Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich | Domain | |
IPR036156 | Beta-Galactosidase/glucuronidase domain superfamily | Homologous Superfamily | |
IPR006104 | Glycosyl hydrolases family 2, sugar binding domain | Domain | |
IPR013783 | Immunoglobulin-like fold | Homologous Superfamily | |
IPR006103 | Glycoside hydrolase family 2, catalytic domain | Domain | |
IPR023232 | Glycoside hydrolase, family 2, active site | Active Site | |
IPR023230 | Glycoside hydrolase, family 2, conserved site | Conserved Site |