Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
A [auth UA]SCOP2B SuperfamilyUTPB complex component-like8056020 3002330 SCOP2B (2022-02-25)
I [auth UL]SCOP2B SuperfamilyUTPB complex component-like8056019 3002330 SCOP2B (2022-02-25)
J [auth UM]SCOP2B SuperfamilyUTPB complex component-like8056022 3002330 SCOP2B (2022-02-25)
O [auth UU]SCOP2B SuperfamilyUTPB complex component-like8056021 3002330 SCOP2B (2022-02-25)
R [auth CA]SCOP2B SuperfamilyS-adenosyl-L-methionine-dependent methyltransferases8065682 3000118 SCOP2B (2022-02-25)
S [auth CB]SCOP2B SuperfamilyS-adenosyl-L-methionine-dependent methyltransferases8065682 3000118 SCOP2B (2022-02-25)
V [auth CE]SCOP2B SuperfamilyL30e-like8063954 3001739 SCOP2B (2022-02-25)
W [auth CF]SCOP2B SuperfamilyL30e-like8063954 3001739 SCOP2B (2022-02-25)
BA [auth CK]SCOP2B SuperfamilyClass II aaRS ABD-related8095989 3000465 SCOP2B (2022-02-25)
BA [auth CK]SCOP2B SuperfamilyClass II aaRS ABD-related8095988 3000465 SCOP2B (2022-02-25)
EA [auth CN]SCOP2B Superfamilyalpha/beta knot8094639 3001122 SCOP2B (2022-02-25)
FA [auth CO]SCOP2B Superfamilyalpha/beta knot8094639 3001122 SCOP2B (2022-02-25)
LA [auth Ca]SCOP2B SuperfamilyRibosomal S3Ae-like8094667 3002166 SCOP2B (2022-02-25)
NA [auth Cc]SCOP2B SuperfamilyRibosomal protein S78095683 3000799 SCOP2B (2022-02-25)
TA [auth Ci]SCOP2 FamilyRibosomal protein L18p and S118095756 4000555 SCOP2 (2022-02-25)
TA [auth Ci]SCOP2 SuperfamilyTranslational machinery components8095757 3000571 SCOP2 (2022-02-25)
UA [auth Cj]SCOP2B SuperfamilyRibosomal protein S5 domain 2-like8097794 3000100 SCOP2B (2022-02-25)
WA [auth Cm]SCOP2 FamilyRibosomal protein S88095562 4002027 SCOP2 (2022-02-25)
WA [auth Cm]SCOP2 SuperfamilyRibosomal protein S88095563 3000709 SCOP2 (2022-02-25)
YA [auth Co]SCOP2B SuperfamilyRibosomal proteins S24e L23 and L15e8098446 3000210 SCOP2B (2022-02-25)
ZA [auth Cp]SCOP2B SuperfamilyNucleic acid-binding proteins8095187 3000135 SCOP2B (2022-02-25)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth UA]ANAPC4_WD40_6e6rxvUA2 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: ANAPC4_WD40_6ECOD (1.6)
A [auth UA]ANAPC4_WD40_4e6rxvUA3 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: ANAPC4_WD40_4ECOD (1.6)
A [auth UA]Utp12e6rxvUA1 A: alpha superhelicesX: Repetitive alpha hairpinsH: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology)T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13F: Utp12ECOD (1.6)
D [auth UD]ANAPC4_WD40_9e6rxvUD1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: ANAPC4_WD40_9ECOD (1.6)
D [auth UD]ANAPC4_WD40_4e6rxvUD2 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: ANAPC4_WD40_4ECOD (1.6)
E [auth UF]TPR_11_6e6rxvUF1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: TPR_11_6ECOD (1.6)
J [auth UM]ANAPC4_WD40_7e6rxvUM3 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: ANAPC4_WD40_7ECOD (1.6)
J [auth UM]ANAPC4_WD40_10e6rxvUM2 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: ANAPC4_WD40_10ECOD (1.6)
J [auth UM]Utp13e6rxvUM1 A: alpha superhelicesX: Repetitive alpha hairpinsH: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology)T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13F: Utp13ECOD (1.6)
O [auth UU]ANAPC4_WD40_9e6rxvUU3 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: ANAPC4_WD40_9ECOD (1.6)
O [auth UU]Utp21e6rxvUU1 A: alpha superhelicesX: Repetitive alpha hairpinsH: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology)T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13F: Utp21ECOD (1.6)
Q [auth UZ]Ribosomal_L1_2nde6rxvUZ1 A: a+b two layersX: a+b domain in Ribosomal protein L1 (From Topology)H: a+b domain in Ribosomal protein L1 (From Topology)T: a+b domain in Ribosomal protein L1F: Ribosomal_L1_2ndECOD (1.6)
Q [auth UZ]Ribosomal_L1_1st_2e6rxvUZ2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Rossmann-like domain in Ribosomal protein L1 (From Topology)T: Rossmann-like domain in Ribosomal protein L1F: Ribosomal_L1_1st_2ECOD (1.6)
R [auth CA]Fibrillarine6rxvCA1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: FibrillarinECOD (1.6)
S [auth CB]Fibrillarine6rxvCB1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: FibrillarinECOD (1.6)
T [auth CC]Nop_Ce6rxvCC3 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: Nop C-terminal domainF: Nop_CECOD (1.6)
T [auth CC]Nop_Ne6rxvCC1 A: alpha complex topologyX: Nop N-terminal domain (From Topology)H: Nop N-terminal domain (From Topology)T: Nop N-terminal domainF: Nop_NECOD (1.6)
T [auth CC]NOP5NTe6rxvCC2 A: mixed a+b and a/bX: Nop N-terminal domain (From Topology)H: Nop N-terminal domain (From Topology)T: Nop N-terminal domainF: NOP5NTECOD (1.6)
V [auth CE]Ribosomal_L7Ae_1e6rxvCE1 A: a+b three layersX: Bacillus chorismate mutase-likeH: L30e-like (From Topology)T: L30e-likeF: Ribosomal_L7Ae_1ECOD (1.6)
W [auth CF]Ribosomal_L7Ae_1e6rxvCF1 A: a+b three layersX: Bacillus chorismate mutase-likeH: L30e-like (From Topology)T: L30e-likeF: Ribosomal_L7Ae_1ECOD (1.6)
Y [auth CH]RTCe6rxvCH2 A: a+b two layersX: IF3-likeH: EPT/RTPC-like (From Topology)T: EPT/RTPC-likeF: RTCECOD (1.6)
Y [auth CH]RTC_inserte6rxvCH1 A: a+b three layersX: Thioredoxin-likeH: RNA 3'-terminal phosphate cyclase, RPTC, insert domain (From Topology)T: RNA 3'-terminal phosphate cyclase, RPTC, insert domainF: RTC_insertECOD (1.6)
AA [auth CJ]S4e6rxvCJ1 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Alpha-L RNA-binding motifF: S4ECOD (1.6)
EA [auth CN]EMG1e6rxvCN1 A: a/b three-layered sandwichesX: alpha/beta knot (From Topology)H: alpha/beta knot (From Topology)T: alpha/beta knotF: EMG1ECOD (1.6)
FA [auth CO]EMG1e6rxvCO1 A: a/b three-layered sandwichesX: alpha/beta knot (From Topology)H: alpha/beta knot (From Topology)T: alpha/beta knotF: EMG1ECOD (1.6)
HA [auth CQ]KH_1e6rxvCQ1 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: KH-domainsT: Eukaryotic type KH-domain (KH-domain type I)F: KH_1ECOD (1.6)
HA [auth CQ]KOG3273e6rxvCQ2 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: KH-domainsT: Eukaryotic type KH-domain (KH-domain type I)F: KOG3273ECOD (1.6)
IA [auth CR]tRNA_bind_2e6rxvCR4 A: alpha arraysX: HTHH: HTHT: tri-helicalF: tRNA_bind_2ECOD (1.6)
IA [auth CR]GNAT_acetyltr_2e6rxvCR1 A: a+b three layersX: Nat/IvyH: Acyl-CoA N-acyltransferases (Nat) (From Topology)T: Acyl-CoA N-acyltransferases (Nat)F: GNAT_acetyltr_2ECOD (1.6)
IA [auth CR]DUF1726e6rxvCR2 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: DUF1726ECOD (1.6)
IA [auth CR]Helicase_RecDe6rxvCR3 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: Helicase_RecDECOD (1.6)
JA [auth CS]tRNA_bind_2e6rxvCS4 A: alpha arraysX: HTHH: HTHT: tri-helicalF: tRNA_bind_2ECOD (1.6)
JA [auth CS]GNAT_acetyltr_2e6rxvCS1 A: a+b three layersX: Nat/IvyH: Acyl-CoA N-acyltransferases (Nat) (From Topology)T: Acyl-CoA N-acyltransferases (Nat)F: GNAT_acetyltr_2ECOD (1.6)
JA [auth CS]DUF1726e6rxvCS2 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: DUF1726ECOD (1.6)
JA [auth CS]Helicase_RecDe6rxvCS3 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: Helicase_RecDECOD (1.6)
LA [auth Ca]Ribosomal_S3Ae_Ne6rxvCa2 A: beta barrelsX: Ribosomal protein L25-likeH: 40S ribosomal protein S3A N-terminal domain (From Topology)T: 40S ribosomal protein S3A N-terminal domainF: Ribosomal_S3Ae_NECOD (1.6)
LA [auth Ca]Ribosomal_S3Ae_Ce6rxvCa1 A: a+b two layersX: T-foldH: 40S ribosomal protein S3A C-terminal domain (From Topology)T: 40S ribosomal protein S3A C-terminal domainF: Ribosomal_S3Ae_CECOD (1.6)
MA [auth Cb]Ribosomal_S4ee6rxvCb1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: Ribosomal_S4eECOD (1.6)
MA [auth Cb]40S_S4_Ce6rxvCb2 A: beta barrelsX: SH3H: SH3T: SH3F: 40S_S4_CECOD (1.6)
MA [auth Cb]RS4NTe6rxvCb3 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Alpha-L RNA-binding motifF: RS4NTECOD (1.6)
NA [auth Cc]Ribosomal_S7_1e6rxvCc1 A: alpha arraysX: Ribosomal protein S7 (From Topology)H: Ribosomal protein S7 (From Topology)T: Ribosomal protein S7F: Ribosomal_S7_1ECOD (1.6)
OA [auth Cd]Ribosomal_S6ee6rxvCd1 A: beta barrelsX: Ribosomal protein L25-likeH: Ribosomal protein L25-like (From Topology)T: Ribosomal protein L25-likeF: Ribosomal_S6eECOD (1.6)
PA [auth Ce]Ribosomal_S7e_Ce6rxvCe1 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: 40S ribosomal protein S7-A (From Topology)T: 40S ribosomal protein S7-AF: Ribosomal_S7e_CECOD (1.6)
PA [auth Ce]Ribosomal_S7e_Ne6rxvCe2 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: 40S ribosomal protein S7-A (From Topology)T: 40S ribosomal protein S7-AF: Ribosomal_S7e_NECOD (1.6)
QA [auth Cf]Ribosomal_S8ee6rxvCf1 A: beta barrelsX: Ribosomal protein L14-likeH: Ribosomal protein L14-related (From Topology)T: Ribosomal protein L14-relatedF: Ribosomal_S8eECOD (1.6)
RA [auth Cg]S4e6rxvCg1 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Alpha-L RNA-binding motifF: S4ECOD (1.6)
SA [auth Ch]Ribosomal_S15_2e6rxvCh1 A: alpha arraysX: S15/NS1 RNA-binding domain (From Topology)H: S15/NS1 RNA-binding domain (From Topology)T: S15/NS1 RNA-binding domainF: Ribosomal_S15_2ECOD (1.6)
TA [auth Ci]Ribosomal_S11e6rxvCi1 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: Ribosomal_S11ECOD (1.6)
UA [auth Cj]Ribosomal_S9e6rxvCj1 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: Ribosomal_S9ECOD (1.6)
VA [auth Ck]Ribosomal_S17_1e6rxvCk1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: Ribosomal_S17_1ECOD (1.6)
WA [auth Cm]Ribosomal_S8_N_1e6rxvCm1 A: a+b two layersX: R3H domain-likeH: Ribosomal protein S8, N-terminal domain (From Topology)T: Ribosomal protein S8, N-terminal domainF: Ribosomal_S8_N_1ECOD (1.6)
WA [auth Cm]Ribosomal_S8_C_1e6rxvCm2 A: a+b two layersX: Ribosomal protein S8, C-terminal domain (From Topology)H: Ribosomal protein S8, C-terminal domain (From Topology)T: Ribosomal protein S8, C-terminal domainF: Ribosomal_S8_C_1ECOD (1.6)
XA [auth Cn]Ribosom_S12_S23e6rxvCn1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: Ribosom_S12_S23ECOD (1.6)
YA [auth Co]Ribosomal_S24ee6rxvCo1 A: a+b two layersX: Alpha-beta plaitsH: Ribosomal proteins S24e, L23 and L15e (From Topology)T: Ribosomal proteins S24e, L23 and L15eF: Ribosomal_S24eECOD (1.6)
ZA [auth Cp]Ribosomal_S28ee6rxvCp1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: Ribosomal_S28eECOD (1.6)
DB [auth UV]Nrap_D2e6rxvUV5 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: PAP/OAS1 substrate-binding domainF: Nrap_D2ECOD (1.6)
DB [auth UV]Nrap_D5e6rxvUV6 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: PAP/OAS1 substrate-binding domainF: Nrap_D5ECOD (1.6)
DB [auth UV]Nrap_D3e6rxvUV1 A: a+b two layersX: Alpha-beta plaitsH: PAP/Archaeal CCA-adding enzyme, C-terminal domain (From Topology)T: PAP/Archaeal CCA-adding enzyme, C-terminal domainF: Nrap_D3ECOD (1.6)
DB [auth UV]UNK_F_TYPEe6rxvUV2 A: a+b two layersX: Alpha-beta plaitsH: PAP/Archaeal CCA-adding enzyme, C-terminal domain (From Topology)T: PAP/Archaeal CCA-adding enzyme, C-terminal domainF: UNK_F_TYPEECOD (1.6)
DB [auth UV]Nrape6rxvUV4 A: a+b three layersX: Nucleotidyltransferase-likeH: Nucleotidyltransferase (From Topology)T: NucleotidyltransferaseF: NrapECOD (1.6)
DB [auth UV]Nrap_D4e6rxvUV3 A: a+b three layersX: Nucleotidyltransferase-likeH: Nucleotidyltransferase (From Topology)T: NucleotidyltransferaseF: Nrap_D4ECOD (1.6)
EB [auth CV]KOG4008,Peripla_BP_4_Ce6rxvCV1 A: a+b two layersX: Alpha-beta plaitsH: RNA-binding domain, RBD (From Topology)T: RNA-binding domain, RBDF: KOG4008,Peripla_BP_4_CECOD (1.6)
FB [auth CW]ANAPC4_WD40_5e6rxvCW1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 8-bladedF: ANAPC4_WD40_5ECOD (1.6)
IB [auth UE]UNK_F_TYPEe6rxvUE1 A: alpha superhelicesX: Repetitive alpha hairpinsH: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology)T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13F: UNK_F_TYPEECOD (1.6)
OB [auth UI]UNK_F_TYPEe6rxvUI1 A: alpha superhelicesX: Repetitive alpha hairpinsH: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology)T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13F: UNK_F_TYPEECOD (1.6)
KB [auth Cl]Ribosomal_S13e6rxvCl1 A: alpha arraysX: HhH/H2THH: H2TH (From Topology)T: H2THF: Ribosomal_S13ECOD (1.6)
LB [auth CX]Bystine6rxvCX1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: BystinECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionIdentifierDescriptionCommentsSource
A [auth UA]PF04003Dip2/Utp12 Family (Utp12)Dip2/Utp12 Family- Family
A [auth UA]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
B [auth UB]PF04147Nop14-like family (Nop14)Nop14-like family- Family
C [auth UC]PF09368Sas10 C-terminal domain (Sas10)Sas10 C-terminal domainSas10 is an Essential subunit of U3-containing Small Subunit (SSU) processome complex involved in the production of the 18S rRNA and assembly of the small ribosomal subunit.Domain
D [auth UD]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
E [auth UF]PF08640U3 small nucleolar RNA-associated protein 6 (U3_assoc_6)U3 small nucleolar RNA-associated protein 6- Family
F [auth UG]PF08149BING4CT (NUC141) domain (BING4CT)BING4CT (NUC141) domainThis C terminal domain is found in the BING4 family of nucleolar WD40 repeat proteins [1].Domain
G [auth UJ]PF08146BP28CT (NUC211) domain (BP28CT)BP28CT (NUC211) domainThis C terminal domain is found in BAP28-like nucleolar proteins [1].Domain
G [auth UJ]PF12397U3 small nucleolar RNA-associated protein 10 (U3snoRNP10)U3 small nucleolar RNA-associated protein 10- Family
H [auth UK]PF03998Utp11 protein (Utp11)Utp11 protein- Family
I [auth UL]PF04003Dip2/Utp12 Family (Utp12)Dip2/Utp12 Family- Family
I [auth UL]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
J [auth UM]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
J [auth UM]PF08625Utp13 specific WD40 associated domain (Utp13)Utp13 specific WD40 associated domainUtp13 is a component of the five protein Pwp2 complex that forms part of a stable particle subunit independent of the U3 small nucleolar ribonucleoprotein that is essential for the initial assembly steps of the 90S pre-ribosome [1]. Pwp2 is capable o ...Utp13 is a component of the five protein Pwp2 complex that forms part of a stable particle subunit independent of the U3 small nucleolar ribonucleoprotein that is essential for the initial assembly steps of the 90S pre-ribosome [1]. Pwp2 is capable of interacting directly with the 35 S pre-rRNA 5' end [1].
Domain
K [auth UN]PF04615Utp14 protein (Utp14)Utp14 protein- Family
L [auth UO]PF09384UTP15 C terminal (UTP15_C)UTP15 C terminal- Family
L [auth UO]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
M [auth UQ]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
O [auth UU]PF04192Utp21 specific WD40 associated putative domain (Utp21)Utp21 specific WD40 associated putative domainUtp21 is a subunit of U3 snoRNP, which is essential for synthesis of 18S rRNA.Domain
O [auth UU]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
Q [auth UZ]PF00687Ribosomal protein L1p/L10e family (Ribosomal_L1)Ribosomal protein L1p/L10e familyThis family includes prokaryotic L1 and eukaryotic L10.Domain
R [auth CA],
S [auth CB]
PF01269Fibrillarin (Fibrillarin)Fibrillarin- Domain
T [auth CC]PF08156NOP5NT (NUC127) domain (NOP5NT)NOP5NT (NUC127) domainThis N terminal domain is found in RNA-binding proteins of the NOP5 family [1].Domain
T [auth CC]PF01798snoRNA binding domain, fibrillarin (Nop)snoRNA binding domain, fibrillarin- Family
U [auth CD]PF08156NOP5NT (NUC127) domain (NOP5NT)NOP5NT (NUC127) domainThis N terminal domain is found in RNA-binding proteins of the NOP5 family [1].Domain
U [auth CD]PF01798snoRNA binding domain, fibrillarin (Nop)snoRNA binding domain, fibrillarin- Family
V [auth CE],
W [auth CF]
PF01248Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (Ribosomal_L7Ae)Ribosomal protein L7Ae/L30e/S12e/Gadd45 familyThis family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD11 ...This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118 [1].
Domain
X [auth CG]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
Y [auth CH]PF05189RNA 3'-terminal phosphate cyclase (RTC), insert domain (RTC_insert)RNA 3'-terminal phosphate cyclase (RTC), insert domainRNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the end of RNA, in a reaction involving formation o ...RNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the end of RNA, in a reaction involving formation of the covalent AMP-cyclase intermediate [1]. The structure of RTC demonstrates that RTCs are comprised two domain. The larger domain contains an insert domain of approximately 100 amino acids [1].
Domain
Y [auth CH]PF01137RNA 3'-terminal phosphate cyclase (RTC)RNA 3'-terminal phosphate cyclaseRNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the end of RNA, in a reaction involving formation o ...RNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the end of RNA, in a reaction involving formation of the covalent AMP-cyclase intermediate [1]. The structure of RTC demonstrates that RTCs are comprised two domain. The larger domain contains an insert domain of approximately 100 amino acids [1].
Domain
Z [auth CI]PF08142AARP2CN (NUC121) domain (AARP2CN)AARP2CN (NUC121) domainThis domain is the central domain of AARP2. It is weakly similar to the GTP-binding domain of elongation factor TU [1].Domain
Z [auth CI]PF0495040S ribosome biogenesis protein Tsr1 and BMS1 C-terminal (RIBIOP_C)40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal- Family
AA [auth CJ]PF00163Ribosomal protein S4/S9 N-terminal domain (Ribosomal_S4)Ribosomal protein S4/S9 N-terminal domain- Family
AA [auth CJ]PF01479S4 domain (S4)S4 domainThe S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ...The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation [1]. The S4 domain probably mediates binding to RNA.
Domain
BA [auth CK]PF04427Brix domain (Brix)Brix domain- Domain
CA [auth CL]PF04006Mpp10 protein (Mpp10)Mpp10 protein- Family
DA [auth CM]PF04158Sof1-like domain (Sof1)Sof1-like domain- Family
DA [auth CM]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
EA [auth CN],
FA [auth CO]
PF03587EMG1/NEP1 methyltransferase (EMG1)EMG1/NEP1 methyltransferase- Family
GA [auth CP]PF17903Krr1 KH1 domain (KH_8)Krr1 KH1 domainThis entry represents the first KH domain in the KRR1 protein [1]. Krr1 is a ribosomal assembly factor. The KH1 domain is a divergent KH domain that lacks the RNA-binding GXXG motif and is involved in binding another assembly factor, Kri1 [1].Domain
IA [auth CR],
JA [auth CS]
PF13725Possible tRNA binding domain (tRNA_bind_2)Possible tRNA binding domain- Family
IA [auth CR],
JA [auth CS]
PF08351tRNA(Met) cytidine acetyltransferase TmcA, N-terminal (TmcA_N)tRNA(Met) cytidine acetyltransferase TmcA, N-terminal- Family
IA [auth CR],
JA [auth CS]
PF13718GNAT acetyltransferase 2 (GNAT_acetyltr_2)GNAT acetyltransferase 2- Family
IA [auth CR],
JA [auth CS]
PF05127Helicase (Helicase_RecD)HelicaseThis domain contains a P-loop (Walker A) motif, suggesting that it has ATPase activity, and a Walker B motif. In tRNA(Met) cytidine acetyltransferase (TmcA) it may function as an RNA helicase motor (driven by ATP hydrolysis) which delivers the wobble ...This domain contains a P-loop (Walker A) motif, suggesting that it has ATPase activity, and a Walker B motif. In tRNA(Met) cytidine acetyltransferase (TmcA) it may function as an RNA helicase motor (driven by ATP hydrolysis) which delivers the wobble base to the active centre of the GCN5-related N-acetyltransferase (GNAT) domain [1]. It is found in the bacterial exodeoxyribonuclease V alpha chain (RecD), which has 5'-3' helicase activity. It is structurally similar to the motor domain 1A in other SF1 helicases [2].
Domain
KA [auth CT]PF08698Fcf2 pre-rRNA processing (Fcf2)Fcf2 pre-rRNA processing- Family
LA [auth Ca]PF01015Ribosomal S3Ae family (Ribosomal_S3Ae)Ribosomal S3Ae family- Family
MA [auth Cb]PF00900Ribosomal family S4e (Ribosomal_S4e)Ribosomal family S4e- Family
MA [auth Cb]PF1612140S ribosomal protein S4 C-terminus (40S_S4_C)40S ribosomal protein S4 C-terminus- Family
MA [auth Cb]PF08071RS4NT (NUC023) domain (RS4NT)RS4NT (NUC023) domainThis is the N-terminal domain of Ribosomal S4 / S4e proteins. This domain is associated with S4 and KOW domains [1].Domain
MA [auth Cb]PF01479S4 domain (S4)S4 domainThe S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ...The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation [1]. The S4 domain probably mediates binding to RNA.
Domain
NA [auth Cc]PF00177Ribosomal protein S7p/S5e (Ribosomal_S7)Ribosomal protein S7p/S5eThis family contains ribosomal protein S7 from prokaryotes and S5 from eukaryotes.Domain
OA [auth Cd]PF01092Ribosomal protein S6e (Ribosomal_S6e)Ribosomal protein S6e- Family
PA [auth Ce]PF01251Ribosomal protein S7e (Ribosomal_S7e)Ribosomal protein S7e- Family
QA [auth Cf]PF01201Ribosomal protein S8e (Ribosomal_S8e)Ribosomal protein S8e- Family
RA [auth Cg]PF00163Ribosomal protein S4/S9 N-terminal domain (Ribosomal_S4)Ribosomal protein S4/S9 N-terminal domain- Family
RA [auth Cg]PF01479S4 domain (S4)S4 domainThe S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ...The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation [1]. The S4 domain probably mediates binding to RNA.
Domain
SA [auth Ch]PF00312Ribosomal protein S15 (Ribosomal_S15)Ribosomal protein S15- Domain
TA [auth Ci]PF00411Ribosomal protein S11 (Ribosomal_S11)Ribosomal protein S11- Family
UA [auth Cj]PF00380Ribosomal protein S9/S16 (Ribosomal_S9)Ribosomal protein S9/S16- Family
VA [auth Ck]PF00366Ribosomal protein S17 (Ribosomal_S17)Ribosomal protein S17- Domain
VA [auth Ck]PF16205Ribosomal_S17 N-terminal (Ribosomal_S17_N)Ribosomal_S17 N-terminal- Family
WA [auth Cm]PF00410Ribosomal protein S8 (Ribosomal_S8)Ribosomal protein S8- Domain
XA [auth Cn]PF00164Ribosomal protein S12/S23 (Ribosom_S12_S23)Ribosomal protein S12/S23- Family
YA [auth Co]PF01282Ribosomal protein S24e (Ribosomal_S24e)Ribosomal protein S24e- Family
ZA [auth Cp]PF01200Ribosomal protein S28e (Ribosomal_S28e)Ribosomal protein S28e- Family
AB [auth CU]PF15375Domain of unknown function (DUF4602) (DUF4602)Domain of unknown function (DUF4602)- Family
DB [auth UV]PF03813Nrap protein domain 1 (Nrap)Nrap protein domain 1Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1]. This domain has a nucleotidyltransferase structure.
Domain
DB [auth UV]PF17403Nrap protein PAP/OAS-like domain (Nrap_D2)Nrap protein PAP/OAS-like domainMembers of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1].
Domain
DB [auth UV]PF17406Nrap protein PAP/OAS1-like domain 5 (Nrap_D5)Nrap protein PAP/OAS1-like domain 5Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1].
Domain
DB [auth UV]PF17407Nrap protein domain 6 (Nrap_D6)Nrap protein domain 6Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1].
Domain
DB [auth UV]PF17404Nrap protein domain 3 (Nrap_D3)Nrap protein domain 3Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1].
Domain
DB [auth UV]PF17405Nrap protein nucleotidyltransferase domain 4 (Nrap_D4)Nrap protein nucleotidyltransferase domain 4Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1].
Domain
EB [auth CV]PF17799Rrp7 RRM-like N-terminal domain (RRM_Rrp7)Rrp7 RRM-like N-terminal domainThis domain corresponds to the N-terminal RNA-binding domain found in the Rrp7 protein. It has an RRM-like fold with a circular permutation [1].Domain
EB [auth CV]PF12923Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain (RRP7)Ribosomal RNA-processing protein 7 (RRP7) C-terminal domainRRP7 is an essential protein in yeast that is involved in pre-rRNA processing and ribosome assembly [1]. It is speculated to be required for correct assembly of rpS27 into the pre-ribosomal particle [1-2].Domain
GB [auth UT]PF20416Domain of unknown function (DUF6700) (DUF6700)Domain of unknown function (DUF6700)This putative domain is found in the UTP20 protein which associated with the U3 snRNA.Domain
GB [auth UT]PF07539Down-regulated in metastasis (DRIM)Down-regulated in metastasis- Family
IB [auth UE],
OB [auth UI]
PF04003Dip2/Utp12 Family (Utp12)Dip2/Utp12 Family- Family
JB [auth US]PF03914CBF/Mak21 family (CBF)CBF/Mak21 family- Family
KB [auth Cl]PF00416Ribosomal protein S13/S18 (Ribosomal_S13)Ribosomal protein S13/S18- Family
LB [auth CX]PF05291Bystin (Bystin)Bystin- Family
NB [auth CZ]PF08164Apoptosis-antagonizing transcription factor, C-terminal (TRAUB)Apoptosis-antagonizing transcription factor, C-terminalThis C terminal domain is found in traube proteins [1]. This is the domain of the AATF proteins that interacts with BLOS2 or Ceap, that functions as an adaptor in processes such as protein and vesicle processing and transport, and perhaps transcripti ...This C terminal domain is found in traube proteins [1]. This is the domain of the AATF proteins that interacts with BLOS2 or Ceap, that functions as an adaptor in processes such as protein and vesicle processing and transport, and perhaps transcription.
Domain
PB [auth UP]PF08297U3 snoRNA associated (U3_snoRNA_assoc)U3 snoRNA associated- Family

Gene Product Annotation Gene Product Annotation

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth UA]Periodic tryptophan protein 2-like protein
        B [auth UB]Utp2
          C [auth UC]Utp3
                D [auth UD]Utp4
                      E [auth UF]Utp6
                          F [auth UG]Utp7
                              G [auth UJ]UTP10
                                  H [auth UK]U3 small nucleolar RNA-associated protein 11
                                      I [auth UL]Utp12
                                          J [auth UM]Utp13
                                              K [auth UN]Utp14
                                                  L [auth UO]Utp15
                                                      M [auth UQ]Utp17
                                                            N [auth UR]Utp18
                                                                  O [auth UU]Utp21
                                                                      P [auth UX]Utp24nonenonenone
                                                                      Q [auth UZ]Utp30
                                                                            R [auth CA],
                                                                            S [auth CB]
                                                                            Nop1
                                                                              T [auth CC]Nop56
                                                                                  U [auth CD]Nop58
                                                                                    V [auth CE],
                                                                                    W [auth CF]
                                                                                    Snu13
                                                                                    X [auth CG]Rrp9
                                                                                        Y [auth CH]RNA 3'-terminal phosphate cyclase-like protein
                                                                                        Z [auth CI]Bms1
                                                                                          AA [auth CJ]Imp3
                                                                                              BA [auth CK]Imp4
                                                                                                  CA [auth CL]Mpp10
                                                                                                      DA [auth CM]Sof1
                                                                                                          EA [auth CN],
                                                                                                          FA [auth CO]
                                                                                                          Emg1
                                                                                                            GA [auth CP]KRR1 small subunit processome component
                                                                                                              HA [auth CQ]Pre-rRNA-processing protein PNO1
                                                                                                              IA [auth CR],
                                                                                                              JA [auth CS]
                                                                                                              Kre33
                                                                                                              KA [auth CT]Fcf2
                                                                                                                  LA [auth Ca]40S ribosomal protein S1
                                                                                                                    MA [auth Cb]40S ribosomal protein S4
                                                                                                                      NA [auth Cc]40S ribosomal protein s5-like protein
                                                                                                                        OA [auth Cd]40S ribosomal protein S6
                                                                                                                          PA [auth Ce]40S ribosomal protein S7
                                                                                                                            QA [auth Cf]40S ribosomal protein S8
                                                                                                                              RA [auth Cg]40S ribosomal protein s9-like protein
                                                                                                                                SA [auth Ch]40S ribosomal protein S13-like protein
                                                                                                                                  TA [auth Ci]40S ribosomal protein S14-like protein
                                                                                                                                    UA [auth Cj]40S ribosomal protein S16-like protein
                                                                                                                                      VA [auth Ck]40S ribosomal protein S11-like protein
                                                                                                                                        WA [auth Cm]40S ribosomal protein S22-like protein
                                                                                                                                          XA [auth Cn]40S ribosomal protein s23-like protein
                                                                                                                                            YA [auth Co]40S ribosomal protein S24
                                                                                                                                            ZA [auth Cp]40S ribosomal protein S28-like protein
                                                                                                                                              AB [auth CU]Faf1
                                                                                                                                                    BB [auth C1]35S ribosomal RNAnonenonenone
                                                                                                                                                    CB [auth C2]U3 snoRNAnonenonenone
                                                                                                                                                    DB [auth UV]U3 small nucleolar RNA-associated protein 22
                                                                                                                                                      EB [auth CV]Rrp7
                                                                                                                                                            FB [auth CW]Ribosome biogenesis protein ENP2
                                                                                                                                                                GB [auth UT]Utp20
                                                                                                                                                                      HB [auth UH]Utp8
                                                                                                                                                                          IB [auth UE],
                                                                                                                                                                          OB [auth UI]
                                                                                                                                                                          Utp5
                                                                                                                                                                                JB [auth US]Noc4
                                                                                                                                                                                  KB [auth Cl]Rps18
                                                                                                                                                                                    LB [auth CX]Enp1
                                                                                                                                                                                          MB [auth CY]U3 small nucleolar ribonucleoprotein protein lcp5-like protein
                                                                                                                                                                                                NB [auth CZ]Bfr2
                                                                                                                                                                                                    PB [auth UP]Utp16