A single sulfatase is required for metabolism of colonic mucin O-glycans and intestinal colonization by a symbiotic human gut bacterium (BT1622-S1_20)
Domain Annotation: ECOD Classification ECOD Database Homepage
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| A [auth AAA] | Sulfatase_1 | e7anaAAA1 | A: a/b three-layered sandwiches | X: Alkaline phosphatase-like (From Topology) | H: Alkaline phosphatase-like (From Topology) | T: Alkaline phosphatase-like | F: Sulfatase_1 | ECOD (1.6) |
| B [auth BBB] | Sulfatase_1 | e7anaBBB1 | A: a/b three-layered sandwiches | X: Alkaline phosphatase-like (From Topology) | H: Alkaline phosphatase-like (From Topology) | T: Alkaline phosphatase-like | F: Sulfatase_1 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
| Chains | Accession | Name | Description | Comments | Source |
|---|---|---|---|---|---|
| A [auth AAA], B [auth BBB] | PF16347 | N-sulphoglucosamine sulphohydrolase, C-terminal (SGSH_C) | N-sulphoglucosamine sulphohydrolase, C-terminal | - | Family |
| A [auth AAA], B [auth BBB] | PF01663 | Type I phosphodiesterase / nucleotide pyrophosphatase (Phosphodiest) | Type I phosphodiesterase / nucleotide pyrophosphatase | - | Family |
| A [auth AAA], B [auth BBB] | PF00884 | Sulfatase (Sulfatase) | Sulfatase | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
| Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
|---|---|---|---|---|
| A [auth AAA], B [auth BBB] | N-acetylgalactosamine-6-sulfatase | - | - |
InterPro: Protein Family Classification InterPro Database Homepage
| Chains | Accession | Name | Type |
|---|---|---|---|
| A [auth AAA], B [auth BBB] | IPR024607 | Sulfatase, conserved site | Conserved Site |
| A [auth AAA], B [auth BBB] | IPR052701 | Glycosaminoglycan & Ulvan Degrading Sulfatases | Family |
| A [auth AAA], B [auth BBB] | IPR000917 | Sulfatase, N-terminal | Domain |
| A [auth AAA], B [auth BBB] | IPR017850 | Alkaline-phosphatase-like, core domain superfamily | Homologous Superfamily |
