7Y8O

Structure of ScIRED-R3-V4 from Streptomyces clavuligerus in complex with 5-(3-fluorophenyl)-3,4-dihydro-2H-pyrrole


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APF21761e7y8oA2 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: PF21761ECOD (1.6)
APF03446e7y8oA1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: PF03446ECOD (1.6)
BPF21761e7y8oB1 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: PF21761ECOD (1.6)
BPF03446e7y8oB2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: PF03446ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF21761NADPH-dependent reductive aminase-like, C-terminal domain (RedAm-like_C)NADPH-dependent reductive aminase-like, C-terminal domainThis domain is found at the C-terminal end of NADPH-dependent reductive aminase from Aspergillus oryzae (RedAm) and similar proteins predominantly found in fungi and bacteria. RedAm catalyses the reductive coupling of a broad set of carbonyl compound ...This domain is found at the C-terminal end of NADPH-dependent reductive aminase from Aspergillus oryzae (RedAm) and similar proteins predominantly found in fungi and bacteria. RedAm catalyses the reductive coupling of a broad set of carbonyl compounds with a variety of primary and secondary amines. This protein folds into an N-terminal Rossman domain (Pfam:PF03446) and a C-terminal helical bundle (this entry) connected by a long inter-domain alpha-helix [3].
Domain
A, B
PF03446NAD binding domain of 6-phosphogluconate dehydrogenase (NAD_binding_2)NAD binding domain of 6-phosphogluconate dehydrogenaseThe NAD binding domain of 6-phosphogluconate dehydrogenase adopts a Rossmann fold.Domain