Annotations: 7LAD

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Cytochrome P450	8068663	3001061	SCOP2B (2022-02-25)

Gene Product Annotation Gene Product Annotation

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Cytochrome P450 3A5	catalytic activity monooxygenase activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen aromatase activity steroid hydroxylase activity estrogen 16-alpha-hydroxylase activity binding heme binding tetrapyrrole binding organic cyclic compound binding heterocyclic compound binding iron ion binding ion binding cation binding metal ion binding transition metal ion binding oxygen binding small molecule binding retinoic acid 4-hydroxylase activity	metabolic process toxin metabolic process cellular process secondary metabolic process mycotoxin metabolic process cellular metabolic process aflatoxin metabolic process heterocycle metabolic process organic substance metabolic process organic cyclic compound metabolic process organic heteropentacyclic compound metabolic process demethylation oxidative demethylation	intracellular anatomical structure cytoplasm endoplasmic reticulum endoplasmic reticulum membrane endomembrane system membrane organelle membrane organelle subcompartment nuclear outer membrane-endoplasmic reticulum membrane network organelle membrane-bounded organelle intracellular organelle intracellular membrane-bounded organelle endoplasmic reticulum subcompartment cellular anatomical entity