Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyProtein kinase-like (PK-like)8036673 3000066 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyUbiquitin-like8034485 3000157 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyC2 domain (calcium/lipid-binding domain calb)8040714 3000965 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyARM repeat-like8038595 3000116 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyC2 domain (calcium/lipid-binding domain calb)8040714 3000965 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyUbiquitin-like8034485 3000157 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyProtein kinase-like (PK-like)8036673 3000066 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyARM repeat-like8038595 3000116 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyUbiquitin-like8034485 3000157 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyARM repeat-like8038595 3000116 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyProtein kinase-like (PK-like)8036673 3000066 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyC2 domain (calcium/lipid-binding domain calb)8040714 3000965 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyARM repeat-like8038595 3000116 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyUbiquitin-like8034485 3000157 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyProtein kinase-like (PK-like)8036673 3000066 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyC2 domain (calcium/lipid-binding domain calb)8040714 3000965 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APF00792e8aj8A4 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: C2 domain (From Topology)T: C2 domainF: PF00792ECOD (1.6)
APF00613e8aj8A2 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF00613ECOD (1.6)
APF00794,PF19710e8aj8A3 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: PF00794,PF19710ECOD (1.6)
APF19710e8aj8A5 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: PF19710ECOD (1.6)
APF00454e8aj8A1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: Protein kinaseF: PF00454ECOD (1.6)
CPF00792e8aj8C2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: C2 domain (From Topology)T: C2 domainF: PF00792ECOD (1.6)
CPF00613e8aj8C1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF00613ECOD (1.6)
CPF00794,PF19710e8aj8C4 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: PF00794,PF19710ECOD (1.6)
CPF19710e8aj8C5 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: PF19710ECOD (1.6)
CPF00454e8aj8C3 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: Protein kinaseF: PF00454ECOD (1.6)
EPF00792e8aj8E3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: C2 domain (From Topology)T: C2 domainF: PF00792ECOD (1.6)
EPF00613e8aj8E2 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF00613ECOD (1.6)
EPF00794,PF19710e8aj8E1 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: PF00794,PF19710ECOD (1.6)
EPF19710e8aj8E5 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: PF19710ECOD (1.6)
EPF00454e8aj8E4 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: Protein kinaseF: PF00454ECOD (1.6)
GPF00792e8aj8G3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: C2 domain (From Topology)T: C2 domainF: PF00792ECOD (1.6)
GPF00613e8aj8G1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF00613ECOD (1.6)
GPF00794,PF19710e8aj8G2 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: PF00794,PF19710ECOD (1.6)
GPF19710e8aj8G5 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: PF19710ECOD (1.6)
GPF00454e8aj8G4 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: Protein kinaseF: PF00454ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, C, E, G
PF00792Phosphoinositide 3-kinase C2 (PI3K_C2)Phosphoinositide 3-kinase C2Phosphoinositide 3-kinase region postulated to contain a C2 domain. Outlier of Pfam:PF00168 family.Domain
A, C, E, G
PF00794PI3-kinase family, ras-binding domain (PI3K_rbd)PI3-kinase family, ras-binding domainCertain members of the PI3K family possess Ras-binding domains in their N-termini. These regions show some similarity (although not highly significant similarity) to Ras-binding Pfam:PF00788 domains (unpublished observation).Domain
A, C, E, G
PF00454Phosphatidylinositol 3- and 4-kinase (PI3_PI4_kinase)Phosphatidylinositol 3- and 4-kinase- Family
B, D, F, H
PF10486Phosphoinositide 3-kinase gamma adapter protein p101 subunit (PI3K_1B_p101)Phosphoinositide 3-kinase gamma adapter protein p101 subunit- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, C, E, G
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
B, D, F, H
Phosphoinositide 3-kinase regulatory subunit 6