8FE1
Alpha1/BetaB Heteromeric Glycine Receptor in 1 mM Glycine 20 uM Ivermectin State
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | F_UNCLASSIFIED | e8fe1A2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Nicotinic receptor ligand binding domain-like (From Topology) | T: Nicotinic receptor ligand binding domain-like | F: F_UNCLASSIFIED | ECOD (1.6) |
A | F_UNCLASSIFIED | e8fe1A1 | A: alpha bundles | X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology) | H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology) | T: Neurotransmitter-gated ion-channel transmembrane pore | F: F_UNCLASSIFIED | ECOD (1.6) |
B [auth D] | F_UNCLASSIFIED | e8fe1D1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Nicotinic receptor ligand binding domain-like (From Topology) | T: Nicotinic receptor ligand binding domain-like | F: F_UNCLASSIFIED | ECOD (1.6) |
B [auth D] | F_UNCLASSIFIED | e8fe1D2 | A: alpha bundles | X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology) | H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology) | T: Neurotransmitter-gated ion-channel transmembrane pore | F: F_UNCLASSIFIED | ECOD (1.6) |
C | F_UNCLASSIFIED | e8fe1C1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Nicotinic receptor ligand binding domain-like (From Topology) | T: Nicotinic receptor ligand binding domain-like | F: F_UNCLASSIFIED | ECOD (1.6) |
C | F_UNCLASSIFIED | e8fe1C2 | A: alpha bundles | X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology) | H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology) | T: Neurotransmitter-gated ion-channel transmembrane pore | F: F_UNCLASSIFIED | ECOD (1.6) |
D [auth B] | F_UNCLASSIFIED | e8fe1B1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Nicotinic receptor ligand binding domain-like (From Topology) | T: Nicotinic receptor ligand binding domain-like | F: F_UNCLASSIFIED | ECOD (1.6) |
D [auth B] | F_UNCLASSIFIED | e8fe1B2 | A: alpha bundles | X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology) | H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology) | T: Neurotransmitter-gated ion-channel transmembrane pore | F: F_UNCLASSIFIED | ECOD (1.6) |
E | F_UNCLASSIFIED | e8fe1E2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Nicotinic receptor ligand binding domain-like (From Topology) | T: Nicotinic receptor ligand binding domain-like | F: F_UNCLASSIFIED | ECOD (1.6) |
E | F_UNCLASSIFIED | e8fe1E1 | A: alpha bundles | X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology) | H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology) | T: Neurotransmitter-gated ion-channel transmembrane pore | F: F_UNCLASSIFIED | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A, B [auth D], C, D [auth B] | PF02932 | Neurotransmitter-gated ion-channel transmembrane region (Neur_chan_memb) | Neurotransmitter-gated ion-channel transmembrane region | - | Family |
A, B [auth D], C, D [auth B] | PF02931 | Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD) | Neurotransmitter-gated ion-channel ligand binding domain | - | Family |
PF02932 | Neurotransmitter-gated ion-channel transmembrane region (Neur_chan_memb) | Neurotransmitter-gated ion-channel transmembrane region | - | Family | |
PF02931 | Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD) | Neurotransmitter-gated ion-channel ligand binding domain | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Membrane Protein Annotation: OPM OPM Database Homepage
Chains | External Link | Type | Class | Superfamily | Family |
---|---|---|---|---|---|
OPM | Transmembrane | Alpha-helical polytopic | Pentameric ligand-gated ion channels | Ligand-gated ion channel of neurotransmitter receptors |
Membrane Protein Annotation: PDBTM PDBTM Database Homepage
Chains | External Link | Comment |
---|---|---|
PDBTM | Annotated as membrane protein by PDBTM |
Membrane Protein Annotation: mpstruc mpstruc Database Homepage
Chains | Resource Link | Group | Subgroup | Protein |
---|---|---|---|---|
mpstruc | TRANSMEMBRANE PROTEINS: ALPHA-HELICAL | Cys-Loop Receptor Family | α1βBheteromeric Glycine Receptor, strychnine-bound state |