Biological Process

What Biological Process are included here?

Vocabulary terms describing biological processes, developed by the Gene Ontology Consortium (GO), are used to organize PDB structures in this browser. Biological processes are mapped to PDB entities based on their UniProt sequences and using the Structure integration with function, taxonomy and sequence (SIFTS) project. These processes are listed in this browse tree only if they have a protein in a PDB structure mapped to it.

Why browse by Biological Process?

Browsing through this tree can help identify protein entities that are involved in the same or related biological processes. You can examine the structures grouped together by the processes they participate in to see if there are any common features or other trends in these proteins.

How to use the Biological Process Browser ?

The Biological Process browser allows users to type in a process name in the search box, select a GO term, or enter a 7-digit GO ID to find polymers of interest.

After locating the biological process of interest in the browser, users can view the number of polymers in this group. Clicking on the numbers listed next to the process name will launch a search for all polymer entities in the PDB that are associated with that biological process.

Example

Browse entities related to insulin signaling, intracellular signaling mediated by an enzyme linked hormone receptor protein signaling as follows:

  • Navigate through the tree and its branches for “signal transduction” >> “cell surface receptor signaling pathway” >> “enzyme linked receptor protein signaling pathway” and “insulin receptor signaling pathway” OR
  • Type insulin in the search box on the top of the page and select from the options “insulin receptor signaling pathway”. OR
  • Type in the 7-digit GO ID: 0008286. If you begin typing the ID 8286, in the search box on the top of the page, autocomplete suggestions will appear, from which you can select the appropriate options to search through the browser tree.


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Last updated: 6/25/2024