Document Search for allosteric regulator
Basic Search"Documentation" mode search results are separated into tabs: “RCSB PDB”, “News/Announcements”, “PDB101”, and “All” (representing all results). Examples Basic search for “allosteric regulator” in the 3D Structure |
Glossarysimilarity in amino acid or bases, respectively. allosteric protein - A protein that changes among two or more structural conformations upon binding to a small molecule called an effector. This binding |
Molecule of the Month: Pyruvate Kinase M2. If more energy is required, fructose bisphosphate (a molecule formed earlier in glycolysis) promotes tetramer formation. A variety of other regulatory molecules can bind to specific allosteric sites |
Geis Archive: ATCase T-stateATCase T-state 1988, 9 1/4" x 10 1/2" In this painting of ATCase T-state, CTP (represented by a shaded hexagonal ring of cytosine) is shown moving into allosteric binding pockets within the |
Molecule of the Month: O-GlcNAc Transferasethe continuous breakdown of obsolete proteins by the ubiquitin/proteasome system. Others, such as the modulation of enzyme function by allosteric motions, are far more subtle and respond to the second |
Molecule of the Month: Isocitrate Dehydrogenasechains (colored turquoise here) perform the reaction, and four regulatory chains (colored dark blue here) turn the enzyme on and off based on the levels of ATP and ADP in our cells. Bacteria take a |
Molecule of the Month: cAMP-dependent Protein Kinase (PKA)protein kinase A or PKA (PDB entries 3tnp , 1j3h and 2h9r ). It is composed of two types of subunits. The catalytic subunit, shown here in pink, performs the phosphate-adding reaction. The regulatory |
Molecule of the Month: SirtuinsWhile studying a rather obscure gene regulatory protein, called Sir2, researchers made a startling discovery. If they engineered yeast cells to produce much higher than normal levels of Sir2, the |
Molecule of the Month: Glycogen Phosphorylaseis needed. Allosteric motion of glycogen phosphorylase: inactive T state (left) and active R state (right). Download high quality TIFF image Shape-shifting Glycogen phosphorylase is activated by a |
Molecule of the Month: Aspartate TranscarbamoylaseMolecule of the Month: Aspartate Transcarbamoylase Key biosynthetic enzymes are regulated by their ultimate products through allosteric motions. Aspartate transcarbamylase, with catalytic subunits in |
Molecule of the Month: Ribonucleotide Reductase) and two beta subunits (green). A nucleotide (red) is bound in a regulatory site in this structure. Download high quality TIFF image DNA and RNA are almost identical in structure, but one small |
Molecule of the Month: ZAR1 Resistosomeamino acid with an available hydroxyl group such as a threonine or serine. Once inside the plant cell, AvrAC starts its attack by adding uridyl groups to regulatory kinase enzymes, which inhibits immune |
Molecule of the Month: Glycolytic Enzymesneeded. Within glycolysis, you will find examples of allosteric enzymes that change shape during their function; enzymes that form covalent bonds to their substrates during the reaction; and enzymes that |
Basic Search"Documentation" mode search results are separated into tabs: “RCSB PDB”, “News/Announcements”, “PDB101”, and “All” (representing all results). Examples Basic search for “allosteric regulator” in the 3D Structure |
PDB-101: Molecule of the Month: Pyruvate Kinase M2. If more energy is required, fructose bisphosphate (a molecule formed earlier in glycolysis) promotes tetramer formation. A variety of other regulatory molecules can bind to specific allosteric sites |
PDB-101: Geis Archive: ATCase T-stateATCase T-state 1988, 9 1/4" x 10 1/2" In this painting of ATCase T-state, CTP (represented by a shaded hexagonal ring of cytosine) is shown moving into allosteric binding pockets within the |
PDB-101: Molecule of the Month: O-GlcNAc Transferasethe continuous breakdown of obsolete proteins by the ubiquitin/proteasome system. Others, such as the modulation of enzyme function by allosteric motions, are far more subtle and respond to the second |
PDB-101: Molecule of the Month: Isocitrate Dehydrogenasechains (colored turquoise here) perform the reaction, and four regulatory chains (colored dark blue here) turn the enzyme on and off based on the levels of ATP and ADP in our cells. Bacteria take a |
PDB-101: Molecule of the Month: cAMP-dependent Protein Kinase (PKA)protein kinase A or PKA (PDB entries 3tnp , 1j3h and 2h9r ). It is composed of two types of subunits. The catalytic subunit, shown here in pink, performs the phosphate-adding reaction. The regulatory |
PDB-101: Molecule of the Month: SirtuinsWhile studying a rather obscure gene regulatory protein, called Sir2, researchers made a startling discovery. If they engineered yeast cells to produce much higher than normal levels of Sir2, the |
PDB-101: Molecule of the Month: Glycogen Phosphorylaseis needed. Allosteric motion of glycogen phosphorylase: inactive T state (left) and active R state (right). Download high quality TIFF image Shape-shifting Glycogen phosphorylase is activated by a |
PDB-101: Molecule of the Month: Aspartate TranscarbamoylaseMolecule of the Month: Aspartate Transcarbamoylase Key biosynthetic enzymes are regulated by their ultimate products through allosteric motions. Aspartate transcarbamylase, with catalytic subunits in |
PDB-101: Molecule of the Month: Ribonucleotide Reductase) and two beta subunits (green). A nucleotide (red) is bound in a regulatory site in this structure. Download high quality TIFF image DNA and RNA are almost identical in structure, but one small |
PDB-101: Molecule of the Month: ZAR1 Resistosomeamino acid with an available hydroxyl group such as a threonine or serine. Once inside the plant cell, AvrAC starts its attack by adding uridyl groups to regulatory kinase enzymes, which inhibits immune |
PDB-101: Molecule of the Month: Glycolytic Enzymesneeded. Within glycolysis, you will find examples of allosteric enzymes that change shape during their function; enzymes that form covalent bonds to their substrates during the reaction; and enzymes that |
Glossarysimilarity in amino acid or bases, respectively. allosteric protein - A protein that changes among two or more structural conformations upon binding to a small molecule called an effector. This binding |
