DPR

D-PROLINE



Chemical Component Summary

NameD-PROLINE
Identifiers(2R)-pyrrolidine-2-carboxylic acid
FormulaC5 H9 N O2
Molecular Weight115.13
TypeD-PEPTIDE LINKING
Isomeric SMILESC1C[C@@H](NC1)C(=O)O
InChIInChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1
InChIKeyONIBWKKTOPOVIA-SCSAIBSYSA-N

Chemical Details

Formal Charge0
Atom Count17
Chiral Atom Count1
Bond Count17
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB02853 
NameD-Proline
Groups experimental
DescriptionD-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva [A19262]. These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity [A19263].
Synonyms
  • (R)-2-Carboxypyrrolidine
  • DPR
  • (2R)-pyrrolidine-2-carboxylic acid
  • D-Proline
  • D-Prolin
CAS number344-25-2

Drug Targets

NameTarget SequencePharmacological ActionActions
Proton-coupled amino acid transporter 1MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWF...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 6971012, 8988
ChEMBL CHEMBL80257
ChEBI CHEBI:16313, CHEBI:57726
CCDC/CSD HUDRAC