GDP

GUANOSINE-5'-DIPHOSPHATE



Chemical Component Summary

NameGUANOSINE-5'-DIPHOSPHATE
Identifiers[(2R,3S,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate
FormulaC10 H15 N5 O11 P2
Molecular Weight443.201
TypeRNA LINKING
Isomeric SMILESc1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
InChIInChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKeyQGWNDRXFNXRZMB-UUOKFMHZSA-N

Chemical Details

Formal Charge0
Atom Count43
Chiral Atom Count4
Bond Count45
Aromatic Bond Count5

Drug Info: DrugBank

DrugBank IDDB04315 
NameGuanosine-5'-Diphosphate
Groups experimental
DescriptionA guanine nucleotide containing two phosphate groups esterified to the sugar moiety. [PubChem]
SynonymsGuanosine-5'-Diphosphate
CAS number146-91-8

Drug Targets

NameTarget SequencePharmacological ActionActions
GTPase HRasMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGET...unknown
Transforming protein RhoAMAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDG...unknown
Protein-glutamine gamma-glutamyltransferase 2MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNY...unknown
Ras-related protein Rab-11AMGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFAT...unknown
Adenylosuccinate synthetaseMGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEK...unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL384759
PubChem 8977, 5280316, 135398619
ChEMBL CHEMBL384759
ChEBI CHEBI:17552