Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Escolano, A., Gristick, H.B., Abernathy, M.E., Merkenschlager, J., Gautam, R., Oliveira, T.Y., Pai, J., West Jr., A.P., Barnes, C.O., Cohen, A.A., Wang, H., Golijanin, J., Yost, D., Keeffe, J.R., Wang, Z., Zhao, P., Yao, K.H., Bauer, J., Nogueira, L., Gao, H., Voll, A.V., Montefiori, D.C., Seaman, M.S., Gazumyan, A., Silva, M., McGuire, A.T., Stamatatos, L., Irvine, D.J., Wells, L., Martin, M.A., Bjorkman, P.J., Nussenzweig, M.C.(2019) Nature 570: 468-473
- PubMed: 31142836 
- DOI: 10.1038/s41586-019-1250-z
- Primary Citation of Related Structures:  
6ORN, 6ORO, 6ORP, 6ORQ - PubMed Abstract: 
Broadly neutralizing monoclonal antibodies protect against infection with HIV-1 in animal models, suggesting that a vaccine that elicits these antibodies would be protective in humans. However, it has not yet been possible to induce adequate serological responses by vaccination ...