Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Zhang, K., Julius, D., Cheng, Y.(2021) Cell 184: 5138-5150.e12
- PubMed: 34496225 
- DOI: https://doi.org/10.1016/j.cell.2021.08.012
- Primary Citation of Related Structures:  
7L2H, 7L2I, 7L2J, 7L2K, 7L2L, 7L2M, 7L2N, 7L2O, 7L2P, 7L2R, 7L2S, 7L2T, 7L2U, 7L2V, 7L2W, 7L2X, 7MZ5, 7MZ6, 7MZ7, 7MZ9, 7MZA, 7MZB, 7MZC, 7MZD, 7MZE - PubMed Abstract: 
Many transient receptor potential (TRP) channels respond to diverse stimuli and conditionally conduct small and large cations. Such functional plasticity is presumably enabled by a uniquely dynamic ion selectivity filter that is regulated by physiological agents ...