Mycobacterium tuberculosis RNAP paused elongation complex with Escherichia coli NusG transcription factor
Delbeau, M., Campbell, E.A., Darst, S.A.To be published.
Experimental Data Snapshot
wwPDB Validation   3D Report Full Report
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
DNA-directed RNA polymerase subunit alpha | A, B | 347 | Mycobacterium tuberculosis | Mutation(s): 0  Gene Names: rpoA EC: 2.7.7.6 | ![]() |
UniProt | |||||
Find proteins for A5U8D3 (Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)) Explore A5U8D3  Go to UniProtKB:  A5U8D3 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | A5U8D3 | ||||
Protein Feature ViewExpand | |||||
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Entity ID: 2 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
DNA-directed RNA polymerase subunit beta | C | 1,172 | Mycobacterium tuberculosis | Mutation(s): 0  Gene Names: rpoB, MRA_0676 EC: 2.7.7.6 | ![]() |
UniProt | |||||
Find proteins for A5U052 (Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)) Explore A5U052  Go to UniProtKB:  A5U052 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | A5U052 | ||||
Protein Feature ViewExpand | |||||
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Entity ID: 3 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
DNA-directed RNA polymerase subunit beta' | D | 1,318 | Mycobacterium tuberculosis | Mutation(s): 0  Gene Names:  rpoC, E5M52_05480, ERS007665_00591, ERS013471_00574, ERS023446_00410, ERS075361_00813, ERS094182_01340, F6W99_03342, E5M05_06640, E5M23_08570... EC: 2.7.7.6 | ![]() |
UniProt | |||||
Find proteins for A0A045J9E2 (Mycobacterium tuberculosis) Explore A0A045J9E2  Go to UniProtKB:  A0A045J9E2 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | A0A045J9E2 | ||||
Protein Feature ViewExpand | |||||
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Entity ID: 4 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
DNA-directed RNA polymerase subunit omega | E | 110 | Mycobacterium tuberculosis | Mutation(s): 0  Gene Names: rpoZ, ERS007703_04032, ERS007720_04749, ERS094182_01030 EC: 2.7.7.6 | ![]() |
UniProt | |||||
Find proteins for A0A0T9N9K3 (Mycobacterium tuberculosis) Explore A0A0T9N9K3  Go to UniProtKB:  A0A0T9N9K3 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | A0A0T9N9K3 | ||||
Protein Feature ViewExpand | |||||
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Entity ID: 5 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Transcription termination/antitermination protein NusG | F [auth N] | 181 | Escherichia coli | Mutation(s): 0  Gene Names: nusG | ![]() |
UniProt | |||||
Find proteins for U9XYQ6 (Escherichia coli 113303) Explore U9XYQ6  Go to UniProtKB:  U9XYQ6 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | U9XYQ6 | ||||
Protein Feature ViewExpand | |||||
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Entity ID: 6 | |||||
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Molecule | Chains | Length | Organism | Image | |
DNA (54-MER) | G [auth O] | 54 | synthetic construct | ![]() | |
Protein Feature ViewExpand | |||||
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Entity ID: 7 | |||||
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Molecule | Chains | Length | Organism | Image | |
DNA (54-MER) | H [auth P] | 54 | synthetic construct | ![]() | |
Protein Feature ViewExpand | |||||
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Entity ID: 8 | |||||
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Molecule | Chains | Length | Organism | Image | |
RNA (42-MER) | I [auth R] | 42 | synthetic construct | ![]() | |
Protein Feature ViewExpand | |||||
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Ligands 2 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
ZN Query on ZN | J [auth D], K [auth D] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N | Ligand Interaction | ||
MG Query on MG | L [auth D] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N | Ligand Interaction |
Funding Organization | Location | Grant Number |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | -- |